A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age

PHASE3RecruitingINTERVENTIONAL
Enrollment

900

Participants

Timeline

Start Date

April 17, 2025

Primary Completion Date

August 3, 2026

Study Completion Date

December 24, 2026

Conditions
Chickenpox
Interventions
BIOLOGICAL

Candidate varicella vaccine

Investigational varicella vaccine administered intramuscularly.

BIOLOGICAL

Marketed varicella vaccine

Marketed varicella vaccine administered subcutaneously.

BIOLOGICAL

MMR vaccine

MMR vaccine administered subcutaneously or intramuscularly.

BIOLOGICAL

Hepatitis A vaccine

Hepatitis A vaccine co-administered intramuscularly.

BIOLOGICAL

PCV (pneumococcal conjugate vaccine) 13

The 13-valent pneumococcal conjugate vaccine co-administered intramuscularly. In some countries PCV will only be administered depending on the availability, country's registration status and national recommendations for pneumococcal vaccination at the time of study conduct.

BIOLOGICAL

PCV 20

The 20-valent pneumococcal conjugate vaccine co-administered intramuscularly. In some countries PCV will only be administered depending on the availability, country's registration status and national recommendations for pneumococcal vaccination at the time of study conduct.

BIOLOGICAL

Vaxneuvance

The Vaxneuvance (15-valent pneumococcal conjugate vaccine) co-administered intramuscularly. In some countries Vaxneuvancewill only be administered depending on the availability, country's registration status and national recommendations for pneumococcal vaccination at the time of study conduct.

Trial Locations (6)

33134

RECRUITING

GSK Investigational Site, Coral Gables

77584

RECRUITING

GSK Investigational Site, Houston

83404

RECRUITING

GSK Investigational Site, Idaho Falls

85704

RECRUITING

GSK Investigational Site, Tucson

90255

RECRUITING

GSK Investigational Site, Huntington Park

91403

RECRUITING

GSK Investigational Site, Sherman Oaks

Sponsors

Lead Sponsor

All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY