60
Participants
Start Date
March 1, 2025
Primary Completion Date
July 1, 2026
Study Completion Date
December 31, 2026
encapsulated 10^4 CFU toxigenic. C. difficile spores
12 consecutive days of once a day a capsule with 10\^4 CFU toxigenic C. difficile spores.
Vancomycin
oral vancomycin pretreatment, 4 times a day 250mg, given the five days before toxigenic C. difficile exposure.
Clindamycin
oral clindamycin pretreatment, 3 times a day 600mg, given the five days before toxigenic C. difficile exposure
Leiden University Medical Center, Leiden
Collaborators (2)
Helmholtz Centre for Infection Research
OTHER
GlaxoSmithKline
INDUSTRY
University of Oxford
OTHER
University of Cologne
OTHER
Leiden University Medical Center
OTHER