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Clinical Trials for Epizyme
Explore 13 clinical trials worldwide
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Showing 1-13 of 13 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Epizyme
Clinical Trials (13)
NCT06068881
"A Study to Assess Efficacy and Safety of Oral Tazemetostat in Adult Participants With Relapsed/Refractory Follicular Lymphoma That Does Not Have an EZH2 Gain-of-function Genetic Mutation"
PHASE2
Not yet recruiting
55 participants
Started: Sep 2, 2025 · Completed: Apr 6, 2029
2 conditions
2 sponsors
0 locations
NCT05994235
Tazemetostat and Mosunetuzumab in Untreated Follicular Lymphoma
PHASE2
Recruiting
50 participants
Started: Nov 1, 2023 · Completed: Oct 31, 2033
1 condition
3 sponsors
1 location
NCT05934838
A Feasibility Trial of Tazemetostat Plus CAR T Cell Therapy in B-cell Lymphomas
PHASE1
Recruiting
15 participants
Started: Oct 4, 2023 · Completed: Sep 30, 2031
4 conditions
4 sponsors
1 location
NCT05407441
Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors
PHASE1/PHASE2
Recruiting
49 participants
Started: Aug 10, 2023 · Completed: Feb 1, 2029
7 conditions
3 sponsors
3 locations
NCT05618366
Tazemetostat and Venetoclax in Relapsed/Refractory Non-Hodgkin Lymphoma
PHASE1
Recruiting
38 participants
Started: Jun 7, 2023 · Completed: Dec 31, 2028
3 conditions
3 sponsors
1 location
NCT05551936
A Study of Tazemetostat With Rituximab and Abbreviated Bendamustine in the Frontline Treatment of High Tumor Burden Follicular Lymphoma
PHASE1/PHASE2
Recruiting
42 participants
Started: Jan 26, 2023 · Completed: May 31, 2027
1 condition
3 sponsors
5 locations
NCT04917042
Tazemetostat in Malignant Peripheral Nerve Sheath Tumors
PHASE2
Active, not recruiting
10 participants
Started: Aug 25, 2021 · Completed: Jan 31, 2026
1 condition
2 sponsors
1 location
NCT04705818
Combining Epigenetic And Immune Therapy to Beat Cancer.
PHASE2
Active, not recruiting
173 participants
Started: Jul 23, 2021 · Completed: Dec 31, 2027
5 conditions
3 sponsors
3 locations
NCT04846478
Phase Ia/Ib Talazoparib + Tazemetostat for mCRPC
PHASE1
Active, not recruiting
35 participants
Started: Jun 28, 2021 · Completed: Sep 30, 2026
2 conditions
4 sponsors
2 locations
NCT04224493
A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.
PHASE3
Recruiting
612 participants
Started: Jun 11, 2020 · Completed: Mar 1, 2029
3 conditions
1 sponsor
222 locations
NCT04241835
A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function
PHASE1
Recruiting
24 participants
Started: Jan 15, 2020 · Completed: Mar 25, 2026
2 conditions
2 sponsors
18 locations
NCT02889523
Study of Tazemetostat in Newly Diagnosed Diffuse Large B Cell and Follicular Lymphoma Patients Treated by Chemiotherapy
PHASE1/PHASE2
Active, not recruiting
214 participants
Started: Oct 31, 2016 · Completed: Apr 30, 2026
3 conditions
2 sponsors
31 locations
NCT02875548
A Study to Assess Long-term Safety of Tazemetostat in Adult Participants of All Ages With Any Disease Treated With Tazemetostat in a Previous Clinical Study
PHASE1/PHASE2
Active, not recruiting
58 participants
Started: Aug 30, 2016 · Completed: Nov 3, 2025
8 conditions
1 sponsor
34 locations