Clinical Trials for Biotheus

Explore 20 clinical trials worldwide

Showing 1-20 of 20 trials

Active filters:Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruitingSponsor: Biotheus

Clinical Trials (20)

NCT07133750
PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer
PHASE2Not yet recruiting
40 participants
Started: Aug 31, 2025 · Completed: Aug 31, 2029
1 condition2 sponsors1 location
NCT07147348
A First-in-human, Dose Escalation and Indication Expansion Study of BNT3212 as Monotherapy or in Combination With BNT327 in Adults With Advanced Solid Tumors
PHASE1/PHASE2Recruiting
375 participants
Started: Aug 27, 2025 · Completed: Mar 31, 2028
1 condition3 sponsors2 locations
NCT06892548
A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer
PHASE1/PHASE2Recruiting
594 participants
Started: May 2, 2025 · Completed: Jun 30, 2031
1 condition3 sponsors12 locations
NCT06827236
A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
PHASE1/PHASE2Recruiting
380 participants
Started: Apr 23, 2025 · Completed: May 31, 2029
3 conditions4 sponsors10 locations
NCT06712355
Safety and Effectiveness of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
PHASE3Active, not recruiting
439 participants
Started: Feb 3, 2025 · Completed: Sep 30, 2028
1 condition2 sponsors57 locations
NCT06712316
Safety, Effectiveness, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
PHASE2/PHASE3Recruiting
982 participants
Started: Jan 7, 2025 · Completed: Dec 31, 2030
1 condition2 sponsors110 locations
NCT06584071
A Study to Evaluate of PM8002 Combined With PM1009 in Patients With First-line HCC
PHASE1/PHASE2Not yet recruiting
140 participants
Started: Dec 31, 2024 · Completed: Dec 31, 2027
2 conditions1 sponsor0 locations
NCT06616532
PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer
PHASE3Recruiting
404 participants
Started: Nov 13, 2024 · Completed: Dec 25, 2028
1 condition1 sponsor45 locations
NCT06419621
PM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/Metastatic TNBC
PHASE3Recruiting
360 participants
Started: Jun 11, 2024 · Completed: Jul 31, 2028
1 condition1 sponsor70 locations
NCT05537051
A Study of PM1021 (Anti-TIGIT) With or Without PM8001 (Anti-PD-L1/TGF-β) in Patients With Advanced Solid Tumours
PHASE1Not yet recruiting
30 participants
Started: Oct 30, 2023 · Completed: Dec 31, 2025
1 condition1 sponsor0 locations
NCT05756972
A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With NSCLC
PHASE2Active, not recruiting
64 participants
Started: Jun 26, 2023 · Completed: Dec 31, 2025
1 condition1 sponsor1 location
NCT05844150
A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC
PHASE2Active, not recruiting
50 participants
Started: Jun 1, 2023 · Completed: Dec 31, 2025
1 condition1 sponsor17 locations
NCT05879055
A Study of PM8002 in Combination With Chemotherapy in Patients With NEN
PHASE2Recruiting
60 participants
Started: May 17, 2023 · Completed: Jan 1, 2028
1 condition1 sponsor13 locations
NCT05918107
A Study of PM8002 Injection in Combination With Standard Chemotherapy as First Line Therapy in MPM
PHASE2Recruiting
55 participants
Started: Aug 13, 2022 · Completed: Jun 30, 2026
1 condition1 sponsor1 location
NCT05839106
Phase I/IIa Study for PM1032 in the Treatment of Patients With Advanced Solid Tumors
PHASE1/PHASE2Recruiting
200 participants
Started: Jul 8, 2022 · Completed: Dec 31, 2025
1 condition1 sponsor3 locations
NCT05918133
A Study of PM8002 Plus Nab-paclitaxel as First Line Therapy for TNBC
PHASE1/PHASE2Active, not recruiting
42 participants
Started: Jul 1, 2022 · Completed: Oct 30, 2026
1 condition1 sponsor8 locations
NCT05879068
A Study of PM8002 in Combination With Chemotherapy in Patients With SCLC
PHASE2Active, not recruiting
99 participants
Started: May 27, 2022 · Completed: Apr 30, 2026
1 condition1 sponsor11 locations
NCT05864105
PM8002 in Combination With Chemotherapy as First Line Therapy in Hepatocellular Carcinoma
PHASE2Active, not recruiting
35 participants
Started: Apr 22, 2022 · Completed: Jun 30, 2026
1 condition1 sponsor9 locations
NCT05862831
Clinical Study of PM1003 in Phase I/IIa Treatment of Advanced Malignant Solid Tumors
PHASE1/PHASE2Recruiting
285 participants
Started: Sep 7, 2021 · Completed: Nov 15, 2025
1 condition1 sponsor2 locations
NCT05918445
PM8002 in the Treatment of Patients With Advanced Solid Tumors
PHASE1/PHASE2Recruiting
380 participants
Started: Mar 9, 2021 · Completed: Nov 30, 2025
1 condition1 sponsor48 locations