A Study of PM1021 (Anti-TIGIT) With or Without PM8001 (Anti-PD-L1/TGF-β) in Patients With Advanced Solid Tumours

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 30, 2023

Primary Completion Date

October 30, 2024

Study Completion Date

December 31, 2025

Conditions
Advanced Solid Tumours
Interventions
DRUG

PM1021, PM8001

Participants will be administered with PM1021 on Part A Day 1. Participants will be administered with PM1021 and PM8001 on Part B Day 1. PM1021 and PM8001 combination therapy administrated every 3 weeks from Part C Day 1 until disease progression, intolerable toxicity, until the patient withdraws/is withdrawn, or study completion.

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Biotheus Inc.

INDUSTRY