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Clinical Trials for AstraZeneca
Explore 800 clinical trials worldwide
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Showing 1-50 of 800 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: AstraZeneca
Clinical Trials (800)
NCT07175415
HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
PHASE1/PHASE2
Not yet recruiting
42 participants
Started: Oct 1, 2026 · Completed: Oct 1, 2032
5 conditions
3 sponsors
0 locations
NCT07162480
Phase II Trial of Puxitatug Samrotecan (AZD8205) in Advanced, Recurrent or Metastatic (R/M) Aggressive Adenoid Cystic Carcinoma Subtype I (ACC-I)
PHASE2
Not yet recruiting
28 participants
Started: Feb 28, 2026 · Completed: Dec 31, 2031
1 condition
2 sponsors
1 location
NCT07049653
Anifrolumab Pregnancy Study
N/A
Not yet recruiting
627 participants
Started: Jan 31, 2026 · Completed: Dec 10, 2030
1 condition
2 sponsors
0 locations
NCT06927648
CAPIVASERTIB REGULATORY POSTMARKETING SURVEILLANCE IN KOREA
N/A
Not yet recruiting
130 participants
Started: Dec 31, 2025 · Completed: Feb 28, 2030
1 condition
1 sponsor
0 locations
NCT07214753
A Real-life Observational Study in Severe Eosinophilic Asthma Adult Participant Treated With Benralizumab in Italy
N/A
Not yet recruiting
335 participants
Started: Dec 19, 2025 · Completed: Dec 31, 2028
1 condition
1 sponsor
28 locations
NCT07215702
A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.
PHASE2
Not yet recruiting
124 participants
Started: Dec 2, 2025 · Completed: Feb 11, 2027
2 conditions
1 sponsor
61 locations
NCT07205666
The Eplontersen Pregnancy and Lactation Outcomes Study
N/A
Not yet recruiting
10 participants
Started: Nov 30, 2025 · Completed: Dec 30, 2035
1 condition
2 sponsors
0 locations
NCT06728410
A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement
PHASE2
Not yet recruiting
38 participants
Started: Nov 30, 2025 · Completed: Jul 31, 2027
3 conditions
4 sponsors
1 location
NCT07069595
PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease
PHASE2
Not yet recruiting
78 participants
Started: Nov 30, 2025 · Completed: Nov 30, 2028
4 conditions
3 sponsors
1 location
NCT06998095
Tezepelumab (Tezspire) Regulatory Postmarketing Surveillance in Korea
N/A
Not yet recruiting
150 participants
Started: Nov 30, 2025 · Completed: Oct 31, 2029
1 condition
1 sponsor
0 locations
NCT07218809
AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer
PHASE3
Not yet recruiting
1,100 participants
Started: Nov 28, 2025 · Completed: May 27, 2030
1 condition
4 sponsors
0 locations
NCT07000110
Anifrolumab Malignancy and Serious Infections Study
N/A
Not yet recruiting
3,506 participants
Started: Nov 28, 2025 · Completed: Nov 30, 2031
1 condition
2 sponsors
0 locations
NCT07201558
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
PHASE1
Not yet recruiting
48 participants
Started: Nov 28, 2025 · Completed: Jun 27, 2028
2 conditions
1 sponsor
0 locations
NCT06705764
Tezepelumab in the Treatment of Emergency Room Asthma in Adults (TERAA)
PHASE4
Not yet recruiting
100 participants
Started: Nov 24, 2025 · Completed: Nov 30, 2026
1 condition
2 sponsors
2 locations
NCT07073950
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD)
PHASE4
Not yet recruiting
56 participants
Started: Nov 14, 2025 · Completed: Mar 31, 2027
2 conditions
2 sponsors
0 locations
NCT07088926
A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization
PHASE2
Not yet recruiting
435 participants
Started: Nov 12, 2025 · Completed: Jun 14, 2028
1 condition
1 sponsor
18 locations
NCT07216131
A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years
PHASE1
Not yet recruiting
14 participants
Started: Nov 10, 2025 · Completed: Dec 29, 2025
1 condition
2 sponsors
0 locations
NCT07155226
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
PHASE1/PHASE2
Not yet recruiting
84 participants
Started: Nov 3, 2025 · Completed: Jun 18, 2029
3 conditions
1 sponsor
13 locations
NCT07215585
AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL
PHASE3
Not yet recruiting
420 participants
Started: Nov 2, 2025 · Completed: Jul 29, 2033
1 condition
1 sponsor
24 locations
NCT07109219
Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia
PHASE1/PHASE2
Not yet recruiting
83 participants
Started: Oct 31, 2025 · Completed: Jul 3, 2028
1 condition
2 sponsors
22 locations
NCT07022483
Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
PHASE3
Not yet recruiting
710 participants
Started: Oct 31, 2025 · Completed: Mar 23, 2032
1 condition
2 sponsors
0 locations
NCT07218536
The Burden of Atypical Hemolytic Uremic Syndrome and The Clinical Characteristics of Patients in Egyptian Hospitals A Multicenter, Observational, Retrospective Cohort Study in Egypt
N/A
Not yet recruiting
200 participants
Started: Oct 31, 2025 · Completed: Sep 30, 2026
1 condition
1 sponsor
0 locations
NCT07123454
A Phase I/II Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
PHASE1/PHASE2
Not yet recruiting
91 participants
Started: Oct 31, 2025 · Completed: Mar 1, 2028
1 condition
1 sponsor
17 locations
NCT06594068
Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in Anifrolumab Users
PHASE4
Recruiting
16 participants
Started: Oct 31, 2025 · Completed: Aug 31, 2027
1 condition
2 sponsors
1 location
NCT07215026
Understanding Non-small Cell Lung Cancer Patient Characteristics, Treatment Patterns and Outcomes
N/A
Not yet recruiting
800 participants
Started: Oct 31, 2025 · Completed: Dec 31, 2025
1 condition
1 sponsor
0 locations
NCT06531798
Post-marketing Phase 4 Safety & Tolerability Study of Breztri aerosphereTM in Indian Patients With Chronic Obstructive Pulmonary Disease
PHASE4
Not yet recruiting
150 participants
Started: Oct 30, 2025 · Completed: Dec 30, 2027
1 condition
1 sponsor
0 locations
NCT07218900
A Study to Investigate the Effect of AZD0780 Tablets in Combination With Rosuvastatin Tablets on Low Density Lipoprotein Cholesterol Levels (LDL-C) in Adult Participants With Dyslipidaemia
PHASE2
Not yet recruiting
76 participants
Started: Oct 24, 2025 · Completed: Sep 30, 2026
1 condition
1 sponsor
8 locations
NCT07161414
A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy
PHASE1
Not yet recruiting
40 participants
Started: Oct 21, 2025 · Completed: Mar 28, 2028
1 condition
2 sponsors
0 locations
NCT07161388
Durvalumab Consolidation After Chemoradiation Therapy for Limited Stage SCLC in China
N/A
Not yet recruiting
200 participants
Started: Oct 15, 2025 · Completed: Apr 30, 2028
1 condition
1 sponsor
1 location
NCT06996782
A Platform Study in Non-Small Cell Lung Cancer (NSCLC)
PHASE1/PHASE2
Not yet recruiting
182 participants
Started: Oct 13, 2025 · Completed: Oct 13, 2028
1 condition
1 sponsor
89 locations
NCT07181161
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
PHASE1/PHASE2
Recruiting
177 participants
Started: Oct 1, 2025 · Completed: Jan 18, 2029
1 condition
2 sponsors
51 locations
NCT07069829
Study of Clinical and Patient-reported Outcomes in Adults With Moderate to Severe COPD Treated With Breztri/Trixeo
N/A
Not yet recruiting
1,400 participants
Started: Sep 30, 2025 · Completed: Sep 30, 2027
1 condition
1 sponsor
0 locations
NCT07149363
Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer
PHASE2
Not yet recruiting
65 participants
Started: Sep 30, 2025 · Completed: Jul 31, 2030
1 condition
2 sponsors
0 locations
NCT06904170
Durvalumab and Tremelimumab With or Without Hepatic Arterial Infusion of Chemotherapy in Hepatocellular Carcinoma
PHASE2/PHASE3
Not yet recruiting
196 participants
Started: Sep 30, 2025 · Completed: Sep 30, 2030
1 condition
2 sponsors
10 locations
NCT07192614
A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer
PHASE1/PHASE2
Recruiting
52 participants
Started: Sep 30, 2025 · Completed: Apr 2, 2029
1 condition
1 sponsor
13 locations
NCT06855225
A Phase II Study of Single Tremelimumab With Regular Interval Durvalumab Plus Gemcitabine and Cisplatin in Locally Advanced Unresectable/Metastatic Combined Hepatocellular-cholangiocarcinoma
PHASE2
Not yet recruiting
29 participants
Started: Sep 30, 2025 · Completed: Apr 30, 2027
1 condition
3 sponsors
0 locations
NCT06880523
STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular Carcinoma
PHASE2
Not yet recruiting
140 participants
Started: Sep 30, 2025 · Completed: Dec 31, 2028
1 condition
3 sponsors
4 locations
NCT07146230
The Selective Personalized Radio-Immunotherapy for Locally Advanced Non-Small Cell Lung Cancer Trial 2
PHASE2
Not yet recruiting
52 participants
Started: Sep 30, 2025 · Completed: Feb 29, 2028
1 condition
2 sponsors
1 location
NCT07205822
A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer
PHASE3
Not yet recruiting
100 participants
Started: Sep 30, 2025 · Completed: Feb 2, 2028
1 condition
2 sponsors
37 locations
NCT06822543
A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer)
PHASE2
Recruiting
46 participants
Started: Sep 30, 2025 · Completed: Nov 1, 2028
3 conditions
3 sponsors
1 location
NCT05888857
MEDI5752 in Patients With Mature Tertiary Lymphoid Structures Solid Tumors.
PHASE2
Not yet recruiting
102 participants
Started: Sep 30, 2025 · Completed: Sep 30, 2028
1 condition
3 sponsors
1 location
NCT06909773
The Prevalence, Disease Burden and Prognosis of COPD in Patients With Cardiovascular Diseases
NA
Not yet recruiting
3,000 participants
Started: Sep 30, 2025 · Completed: Jun 30, 2026
1 condition
1 sponsor
3 locations
NCT07024706
Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab
PHASE2
Not yet recruiting
80 participants
Started: Sep 30, 2025 · Completed: Nov 30, 2032
2 conditions
3 sponsors
0 locations
NCT06795893
The Anifrolumab PRIM Program
N/A
Not yet recruiting
240 participants
Started: Sep 30, 2025 · Completed: Apr 15, 2031
1 condition
2 sponsors
0 locations
NCT07129993
Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma
PHASE2/PHASE3
Recruiting
630 participants
Started: Sep 26, 2025 · Completed: Jan 22, 2030
2 conditions
2 sponsors
5 locations
NCT07058519
A Study of Osimertinib-based Adaptive Treatment Guided by ctDNA EGFRm+ Monitoring in NSCLC
PHASE2
Recruiting
250 participants
Started: Sep 23, 2025 · Completed: Jan 24, 2029
1 condition
2 sponsors
1 location
NCT07157787
Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)
PHASE2
Recruiting
30 participants
Started: Sep 19, 2025 · Completed: Feb 12, 2027
1 condition
2 sponsors
39 locations
NCT07167433
Observational, Bi-directional (Prospective and Retrospective) Study for Patients With Newly Diagnosed Ovarian Cancer Stages IA to IVB, or Persistent or Recurrent Disease From January 2021; Irrespective of Histology
N/A
Recruiting
250 participants
Started: Sep 19, 2025 · Completed: Mar 31, 2026
1 condition
1 sponsor
1 location
NCT06995833
Durvalumab With or Without Olaparib in Patients With Endometrial Cancers Regulatory Post Marketing Surveillance
N/A
Recruiting
50 participants
Started: Sep 19, 2025 · Completed: Jun 29, 2029
1 condition
1 sponsor
1 location
NCT07124000
DESTINY-PANTUMOUR04
N/A
Recruiting
100 participants
Started: Sep 18, 2025 · Completed: Mar 30, 2028
27 conditions
1 sponsor
8 locations
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