Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

July 31, 2027

Study Completion Date

July 31, 2030

Conditions
Small Cell Lung Cancer (SCLC)
Interventions
DRUG

Durvalumab 50 MG/ML

Following surgical removal of their small-cell lung cancer, participants will receive a combination of 1500 mg durvalumab and cisplatin 75 mg/m2 or carboplatin AUC 5 on day 1, and etoposide 100 mg/m2 on days 1, 2, and 3, every 3 weeks for 4 cycles (a total of 12 weeks). Following the combination of chemotherapy and immunotherapy, participants will then receive 1500 mg durvalumab every 4 weeks for 9 cycles (a total of 36 weeks).

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

Alliance Foundation Trials, LLC.

OTHER