A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

May 29, 2024

Primary Completion Date

January 31, 2030

Study Completion Date

January 31, 2030

Conditions
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Interventions
DRUG

Aficamten

Oral Tablet

DRUG

Placebo

Oral Tablet

Trial Locations (38)

10027

RECRUITING

NYP/Columbia University Medical Center, New York

10467

NOT_YET_RECRUITING

Children's Hospital at Montefiore, The Bronx

19104

RECRUITING

Children's Hospital of Philadelphia, Philadelphia

20010

RECRUITING

Children's National Hospital, Washington D.C.

27701

NOT_YET_RECRUITING

Duke Clinical Research Institute, Durham

33155

NOT_YET_RECRUITING

Nicklaus Children's Hospital, Miami

37235

RECRUITING

Vanderbilt University Medical Center, Nashville

38103

RECRUITING

LeBonheur Children's Hospital, Memphis

48109

RECRUITING

University of Michigan, Ann Arbor

48201

RECRUITING

Children's Hospital of Michigan, Detroit

52242

RECRUITING

University of Iowa, Iowa City

53226

NOT_YET_RECRUITING

Children's Wisconsin, Milwaukee

55905

RECRUITING

Mayo Clinic, Rochester

60611

RECRUITING

Ann & Robert H. Lurie Children's Hospital, Chicago

64108

RECRUITING

Children's Mercy Hospital, Kansas City

68198

RECRUITING

University of Nebraska Medical Center, Omaha

70018

RECRUITING

Children's Hospital New Orleans, New Orleans

75390

NOT_YET_RECRUITING

UT Southwestern, Dallas

78723

NOT_YET_RECRUITING

Dell Children's Hospital, Austin

80045

RECRUITING

Children's Hospital Colorado, Aurora

85016

NOT_YET_RECRUITING

Phoenix Children's Hospital, Phoenix

90027

RECRUITING

Children's Hospital Los Angeles, Los Angeles

90095

RECRUITING

University of California, Los Angeles (UCLA), Los Angeles

94158

NOT_YET_RECRUITING

UCSF Benioff Children's Hospital, San Francisco

97239

RECRUITING

Oregon Health & Science University, Portland

07960

RECRUITING

Morristown Medical Center, Morristown

M5G 1E8

NOT_YET_RECRUITING

The Hospital for Sick Children (SickKids), Toronto

Unknown

RECRUITING

Careggi University Hospital, Florence

RECRUITING

NHO Kagoshima Medical Center, Kagoshima

NOT_YET_RECRUITING

University of Osaka Hospital, Osaka

RECRUITING

Kitasato University Hospital, Sagamihara

NOT_YET_RECRUITING

National Cerebral and Cardiovascular Center, Suita

NOT_YET_RECRUITING

Juntendo University Hospital, Tokyo

RECRUITING

Unidad de Cardiología Infantil; Hospital Universitario da Coruña, A Coruña

NOT_YET_RECRUITING

Hospital Sant Joan de Deu, Barcelona

RECRUITING

Alder Hey Children's Hospital, Liverpool

SW3 6NP

NOT_YET_RECRUITING

Evelina Children's Hospital, London

WC1N 3BH

RECRUITING

Great Ormond Street Hospital for Children, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Cytokinetics

INDUSTRY

NCT06412666 - A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM). | Biotech Hunter | Biotech Hunter