87
Participants
Start Date
June 11, 2024
Primary Completion Date
November 30, 2027
Study Completion Date
November 30, 2027
AAV2-GDNF Gene therapy
Bilateral image-guided infusion of AAV2-GDNF into putamen, single dose
Control Surgery
Bilateral partial burr/twist holes without dural penetration
RECRUITING
University of Pennsylvania (Neurology), Philadelphia
RECRUITING
Georgetown University (Neurology), Washington D.C.
RECRUITING
University of North Carolina (Neurology), Chapel Hill
ACTIVE_NOT_RECRUITING
Duke Neurosurgery (Surgical), Durham
NOT_YET_RECRUITING
Duke University (Neurology), Durham
ACTIVE_NOT_RECRUITING
Emory University (Surgical), Atlanta
RECRUITING
Parkinson's Disease and Movement Disorders Center of Boca Raton (Neurology), Boca Raton
ACTIVE_NOT_RECRUITING
Parkinson's Disease Treatment Center of Southwest Florida (Neurology), Port Charlotte
RECRUITING
Vanderbilt University (Neurology), Nashville
ACTIVE_NOT_RECRUITING
Ohio State University (Surgical), Columbus
RECRUITING
Quest Research Institute (Neurology), Farmington Hills
RECRUITING
Michigan State University (Neurology), East Lansing
RECRUITING
University of Wisconsin (Neurology), Madison
NOT_YET_RECRUITING
Rush University Medical Center (Neurology), Chicago
RECRUITING
University of Kansas Medical Center (Neurology), Kansas City
RECRUITING
Houston Methodist (Neurology), Houston
ACTIVE_NOT_RECRUITING
Houston Methodist (Surgical), Houston
RECRUITING
CenExel Rocky Mountain Clinical Research (Neurology), Englewood
NOT_YET_RECRUITING
Cleveland Clinic Lou Ruvo (Neurology), Las Vegas
RECRUITING
Loma Linda University (Neurology), Loma Linda
ACTIVE_NOT_RECRUITING
Loma Linda University (Surgical), Loma Linda
NOT_YET_RECRUITING
UCI Alpha Clinic (Neurology), Irvine
RECRUITING
University of California San Francisco (Neurology), San Francisco
ACTIVE_NOT_RECRUITING
University of San Francisco (Surgical), San Francisco
NOT_YET_RECRUITING
EvergreenHealth Research Department (Neurology), Kirkland
RECRUITING
Massachusetts General Hospital (Neurology), Boston
ACTIVE_NOT_RECRUITING
Massachusetts General Hospital (Surgical), Boston
ACTIVE_NOT_RECRUITING
Charité - Universitätsmedizin Berlin (Surgical), Berlin
RECRUITING
Philipps-Universität Marburg (Neurology), Marburg
RECRUITING
Universitätsklinikum Tübingen (Neurology), Tübingen
ACTIVE_NOT_RECRUITING
Universitätsklinikum Tübingen (Surgical), Tübingen
RECRUITING
Universitätsklinikum Würzburg (Neurology), Würzburg
RECRUITING
Copernicus Podmiot Leczniczy, Szpital św. Wojciecha (Neurology), Gdansk
RECRUITING
Specjalistyczna Praktyka Lekarska Prof. Grzegorz Opala (Neurology), Katowice
RECRUITING
Mazowiecki Szpital Bródnowski (Neurology), Warsaw
ACTIVE_NOT_RECRUITING
Mazowiecki Szpital Bródnowski (Surgical), Warsaw
RECRUITING
Samodzielny Publiczny Szpital Kliniczny im. Prof. W. Orłowskiego CMKP (Neurology), Warsaw
RECRUITING
North Bristol NHS Trust - Southmead Hospital (Neurology), Bristol
ACTIVE_NOT_RECRUITING
University Hospital of Wales (Surgical), Cardiff
Lead Sponsor
Collaborators (1)
Bayer
INDUSTRY
AskBio Inc
INDUSTRY