ZEN003694 Combined With Niraparib in Patients With Metastatic or Recurrent Solid Tumors

PHASE1WithdrawnINTERVENTIONAL
0
Timeline

Start Date

January 23, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2029

Conditions
Ovarian CancerRecurrent Solid Tumors
Interventions
DRUG

ZEN003694

A bromodomain extra-terminal inhibitor (BETi) that blocks a group of proteins called bromodomain and extra-terminal (BET), which may counteract the effect of NSD3 on tumor growth.

DRUG

Niraparib

An anti-cancer medication (PARP inhibitor) used for the treatment of epithelial ovarian, fallopian tube, or primary peritoneal cancer .

Trial Locations (1)

15213

UPMC Magee Womens Hospital, Pittsburgh

Sponsors
All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

collaborator

Zenith Epigenetics

INDUSTRY

lead

Haider Mahdi

OTHER