Orally-active small molecules
Total Trials
11
As Lead Sponsor
6
As Collaborator
5
Total Enrollment
643
NCT02238522
Phase 1 Study Evaluating ZEN003365 in Relapsed/Refractory Lymphoproliferative Malignancies or Relapsed/Refractory AML
Phase: Phase 1
Role: Lead Sponsor
Start: Oct 31, 2014
Completion: Jan 31, 2017
NCT02705469
A Study of ZEN003694 in Patients With Metastatic Castration-Resistant Prostate Cancer
Start: May 31, 2016
Completion: Oct 31, 2017
NCT02711956
A Study of ZEN003694 in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer
Phase: Phase 1/2
Start: Dec 31, 2016
Completion: Nov 30, 2019
NCT03901469
A Study of ZEN003694 and Talazoparib in Patients With Triple Negative Breast Cancer
Phase: Phase 2
Start: Jun 26, 2019
Completion: Mar 7, 2024
NCT04145375
Continuation Protocol for ZEN003694 in Patients Experiencing Clinical Benefit While Enrolled in a ZEN003694 Protocol
Start: Nov 12, 2019
Completion: Dec 31, 2026
NCT04471974
ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Role: Collaborator
Start: Jan 26, 2021
Completion: May 31, 2028
NCT04986423
ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer
Start: Sep 8, 2021
Completion: Jun 30, 2026
NCT05607108
A Study of ZEN003694 in People With Squamous Cell Lung Cancer
Start: Nov 1, 2022
Completion: Nov 30, 2025
NCT05071937
ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer
Start: Apr 21, 2023
Completion: Mar 1, 2033
NCT06161493
ZEN003694 Combined With Niraparib in Patients With Metastatic or Recurrent Solid Tumors
Start: Jan 23, 2024
Completion: Dec 31, 2029
NCT06922318
The COSMYC Trial (COmbined Suppression of MYC)
Start: Aug 19, 2025
Completion: Aug 30, 2031
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