Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

408

Participants

Timeline

Start Date

June 26, 2023

Primary Completion Date

July 1, 2026

Study Completion Date

September 1, 2027

Conditions
SLE
Interventions
DRUG

ESK-001

Oral tablet

DRUG

Placebo

Oral tablet

Trial Locations (169)

100

Investigator Site #8017, Taipei

102

Investigator Site #5523, Tbilisi

112

Investigator Site #5538, Tbilisi

114

Investigator Site #5536, Tbilisi

180

Investigator Site #5534, Tbilisi

504

Investigator Site #3022, Bogotá

622

Investigator Site #8013, Chiayi City

1407

Investigator Site #5522, Sofia

1463

Investigator Site #5547, Sofia

2873

Investigator Site #5602, Pleven

3080

Investigator Site #8016, Seoul

3100

Investigator Site #2514, Mexico City

3699

Investigator Site #4008, Alicante

3720

Investigator Site #2503, Mexico City

4003

Investigator Site #5525, Plovdiv

4032

Investigator Site #5548, Debrecen

4103

Investigator Site #4003, Leipzig

4600

Investigator Site #4011, Køge

5030

Investigator Site #8019, Seoul

6273

Investigator Site #8012, Seoul

6300

Investigator Site #5603, Haskovo

6700

Investigator Site #2506, Mexico City

6720

Investigator Site #2504, Cuauhtémoc

7002

Investigator Site #5529, Rousse

7760

Investigator Site #2508, Madero

8035

Investigator Site #4007, Barcelona

10032

Investigator Site #1088, New York

11001

Investigator Site #1175, Queens

11025

Investigator Site #5530, Bucharest

11057

Investigator Site #5549, Bucharest

11111

Investigator Site #3019, Barranquilla

11172

Investigator Site #5526, Bucharest

11201

Investigator Site #1058, Brooklyn

11490

Investigator Site #8014, Kaohsiung City

13001

Investigator Site #3017, Trujillo

14068

Investigator Site #8007, Anyang-si

14080

Investigator Site #2509, Mexico City

15006

Investigator Site #4013, A Coruña

15023

Investigator Site #3005, Santiago de Surco

15047

Investigator Site #3013, Lima

15102

Investigator Site #3018, San Martín de Porres

15224

Investigator Site #1062, Pittsburgh

15801

Investigator Site #3004, Lima

19114

Investigator Site #1171, Philadelphia

21000

Investigator Site #5543, Split

27000

Investigator Site #2513, Torreón

28207

Investigator Site #1095, Charlotte

28210

Investigator Site #1056, Charlotte

28277

Investigator Site #1173, Charlotte

30328

Investigator Site #1170, Atlanta

30329

Investigator Site #1052, College Park

31000

Investigator Site #2501, Chihuahua City

32117

Investigator Site #1091, Daytona Beach

32713

Investigator Site #1051, DeBary

33014

Investigator Site #1067, Miami Lakes

33020

Investigator Site #1087, Hollywood

33071

Investigator Site #1097, Coral Springs

33134

Investigator Site #1055, Coral Gables

33136

Investigator Site #1060, Miami

33155

Investigator Site #1093, Miami

33176

Investigator Site #1057, Miami

33180

Investigator Site #1048, Aventura

33324

Investigator Site #1090, Plantation

33606

Investigator Site #1089, Tampa

33765

Investigator Site #1045, Clearwater

33825

Investigator Site #1063, Avon Park

34209

Investigator Site #1176, Bradenton

34741

Investigator Site #1135, Kissimmee

36207

Investigator Site #1046, Anniston

38119

Investigator Site #1044, Memphis

40201

Investigator Site #8008, Taichung

40447

Investigator Site #8015, Taichung

41014

Investigator Site #4002, Seville

44160

Investigator Site #2502, Guadalajara

44620

Investigator Site #2512, Guadalajara

44650

Investigator Site #2507, Guadalajara

46010

Investigator Site #4009, Valencia

49241

Investigator Site #8004, Busan

50034

Investigator Site #3014, Medellín

51000

Investigator Site #5542, Rijeka

54769

Investigator Site # 2517, Naucalpan

55131

Investigator Site #4005, Mainz

63017

Investigator Site #1204, Chesterfield

68000

Investigator Site #2510, Oaxaca City

75006

Investigator Site #1195, Carrollton

75154

Investigator Site #1187, Red Oak

76034

Investigator Site #1049, Colleyville

76177

Investigator Site #1071, Fort Worth

77054

Investigator Site #1094, Houston

77095

Investigator Site #1169, Houston

77375

Investigator Site #1194, Tomball

77386

Investigator site #1178, Houston

77388

Investigator Site #1172, Spring

78213

Investigator Site #2505, San Luis Potosí City

78215

Investigator site #1053, San Antonio

78229

Investigator Site #1186, San Antonio

80020

Investigator Site #3011, Barranquilla

80336

Investigator Site #4006, Munich

87102

Investigator Site #1101, Albuquerque

89102

Investigator site #1209, Las Vegas

90720

Investigator Site #1050, Los Alamitos

91345

Investigator Site #1168, Mission Hills

91786

Investigator Site #1061, Upland

92037

Investigator Site #1104, La Jolla

94558

Investigator Site #1174, Napa

97070

Investigator Site #2511, Mérida

Investigator Site #2516, Mérida

110221

Investigator Site #3021, Bogotá

122001

Investigator Site #6004, Haryāna

160012

Investigator Site #6012, Chandigarh

226014

Investigator Site #6011, Lucknow

250001

Investigator Site #3003, Chía

302004

Investigator Site #6013, Jaipur

380005

Investigator Site #6005, Ahmedabad

380006

Investigator Site #6010, Ahmedabad

380013

Investigator Site #6016, Ahmedabad

380015

Investigator Site #6006, Ahmedabad

395001

Investigator Site #6002, Surat

395002

Investigator Site #6003, Surat

411007

Investigator Site #6014, Pune

411057

Investigator Site #6007, Pune

440012

Investigator Site #6008, Nagpur

560010

Investigator Site #6009, Bengaluru

560034

Investigator Site #6001, Bangalore

760035

Investigator Site #3020, Santiago de Cali

7510586

Investigator Site #3006, Providencia

75500587

Investigator Site #3002, Santiago

07871

Investigator Site #1189, Sparta

C1425

Investigator Site #3012, CABA

C1221ADC

Investigator Site #3001, Ciudad Autonoma de Buenos Aires

B1900

Investigator Site #3016, La Plata

T4000BRD

Investigator Site #3009, San Miguel de Tucumán

Investigator Site #3010, San Miguel de Tucumán

T4000

Investigator Site #3015, San Miguel de Tucumán

C1114 AAH

Investigator Site #3023, Buenos Aires

M5500CPH

Investigator Site #3008, Mendoza

Unknown

Investigator Site #5521, Plovdiv

Investigator Site #4012, Aarhus

Investigator Site #5517, Tbilisi

Investigator Site #5544, Gyula

Investigator Site #8003, Angeles City

Investigator Site #8009, Iloilo City

Investigator Site #8011, Lipa City

Investigator Site #8001, Manila

Investigator Site #8010, Manila

Investigator Site #8018, Manila

Investigator Site #8006, Quezon City

0168

Investigator Site #5516, Tbilisi

110 029

Investigator Site # 6015, New Delhi

15-077

Investigator Site #5519, Bialystok

15-297

Investigator Site #5546, Bialystok

15-707

Investigator Site #5518, Bialystok

85-168

Investigator Site #5531, Bydgoszcz

41-902

Investigator Site #5520, Bytom

42-200

Investigator Site #5539, Częstochowa

30-363

Investigator Site #5533, Krakow

05-830

Investigator Site #5537, Nadarzyn

61-397

Investigator Site #5545, Poznan

41-200

Investigator Site #5535, Sosnowiec

71-252

Investigator Site #5532, Szczecin

00-215

Investigator Site #5527, Warsaw

02-637

Investigator Site #5540, Warsaw

50-088

Investigator Site #5528, Wroclaw

00725

Investigator site #3028, Caguas

00909-1908

Investigator site #3029, San Juan

LS1 3EX

Investigator Site #4017, Leeds

NW1 2BU

Investigator Site #4015, London

SE1 7RT

Investigator Site #4016, London

SO16 6YD

Investigator Site #4014, Southampton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Alumis Inc

INDUSTRY