Autoimmune Treatments
Total Trials
11
As Lead Sponsor
As Collaborator
0
Total Enrollment
4,356
NCT05330858
Relative Bioavailability of ESK-001 Tablet Versus Liquid in Healthy Participants
Phase: Phase 1
Role: Lead Sponsor
Start: Mar 17, 2022
Completion: Sep 20, 2022
NCT05431634
Multiple Dose Study to Determine Safety and Tolerability of ESK-001 in Healthy Participants
Start: May 12, 2022
Completion: Dec 31, 2022
NCT05600036
A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Plaque Psoriasis
Phase: Phase 2
Start: Sep 27, 2022
Completion: Jul 25, 2023
NCT05739435
Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis
Start: Jan 17, 2023
Completion: Dec 30, 2026
NCT05953688
POC Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Active Intermediate, Posterior, or Pan NIU
Start: Jun 14, 2023
Completion: Aug 13, 2024
NCT05966480
Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus
Start: Jun 26, 2023
Completion: Sep 1, 2027
NCT06586112
A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis
Phase: Phase 3
Start: Jul 25, 2024
Completion: Dec 31, 2025
NCT06588738
A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001
Start: Aug 20, 2024
NCT06846541
Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis
Start: Jan 8, 2025
Completion: Nov 30, 2028
NCT06952634
An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage
Start: Apr 29, 2025
NCT06962774
An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function
Start: May 9, 2025
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