A Maintenance Therapy Study of Odetiglucan With CDX-1140 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

PHASE1TerminatedINTERVENTIONAL
Enrollment

5

Participants

Timeline

Start Date

December 15, 2022

Primary Completion Date

March 4, 2024

Study Completion Date

March 4, 2024

Conditions
Metastatic Pancreatic Adenocarcinoma
Interventions
BIOLOGICAL

odetiglucan

Odetiglucan is a soluble, β-1,3/1,6 glucan isolated from the cell wall of a proprietary Saccharomyces cerevisiae yeast strain. Odetiglucan acts as a Pathogen-Associated Molecular Pattern (PAMP).

BIOLOGICAL

CDX-1140

A fully human agonist anti-CD40 monoclonal antibody

Trial Locations (4)

10065

Memorial Sloan Kettering Cancer Center, New York

19104

University of Pennsylvania, Abramson Cancer Center, Philadelphia

84112

Huntsman Cancer Institute, University of Utah, Salt Lake City

85258

HonorHealth Research Institute, Scottsdale

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Celldex Therapeutics

INDUSTRY

lead

HiberCell, Inc.

INDUSTRY

NCT05484011 - A Maintenance Therapy Study of Odetiglucan With CDX-1140 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma | Biotech Hunter | Biotech Hunter