NCT05217758View on ClinicalTrials.gov

RESET-medication Glucocorticoid Receptor (GR) Blockade As Disease Modifying Treatment for Depression with Childhood Trauma

PHASE2CompletedINTERVENTIONAL
Enrollment

158

Participants

Timeline

Start Date

December 9, 2021

Primary Completion Date

August 9, 2024

Study Completion Date

November 12, 2024

Conditions
Major Depressive DisorderChildhood Trauma
Interventions
DRUG

Mifepristone

1200 mg/day, once daily, 7 days

DRUG

Placebo

Placebo, once daily, 7 days

Trial Locations (1)

1081HV

Amsterdam UMC, location VUmc, Amsterdam

Sponsors

Collaborators (1)

Corcept Therapeutics
All Listed Sponsors
collaborator

Netherlands Brain Foundation

OTHER

collaborator

Corcept Therapeutics

INDUSTRY

lead

Amsterdam UMC, location VUmc

OTHER