Study of BHV-4157 in Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

350

Participants

Timeline

Start Date

July 31, 2018

Primary Completion Date

December 15, 2020

Study Completion Date

December 23, 2021

Conditions
Alzheimer Disease
Interventions
DRUG

troriluzole

Oral BHV-4157 will be given daily for up to 48 weeks

DRUG

Placebo oral capsule

Oral matching placebo will be given daily for up to 48 weeks

Trial Locations (44)

10032

Columbia University, New York

10468

James J. Peters VAMC, The Bronx

13202

SUNY Upstate Medical University Department of Geriatrics, Syracuse

14620

University of Rochester Medical Center, Rochester

15213

University of Pittsburgh, Pittsburgh

18711

Geisinger Medical Clinic, Wilkes-Barre

19090

Abington Neurological Associates, Willow Grove

19403

Keystone Clinical Studies, LLC, Norristown

21224

Johns Hopkins University, Baltimore

29401

CBRI, Roper Hospital, Charleston

33136

University of Miami, Miami

33445

Brain Matters Research, Delray Beach

33613

USF Health Byrd Alzheimer's Institute, Tampa

37212

Vanderbilt Memory & Alzheimer's Center, Nashville

40504

University of Kentucky, Lexington

43210

Ohio State University, Columbus

44122

Case Western Reserve University, Beachwood

46202

Indiana University, Indianapolis

48105

University of Michigan, Ann Arbor, Ann Arbor

48824

Michigan State University, East Lansing

52242

University of Iowa, Iowa City

60611

Northwestern University, Chicago

60640

Great Lakes Clinical Trials, Chicago

62702

Southern Illinois University, Springfield

63005

Galen Research, Chesterfield

70808

Pennington Biomedical Research Center, Baton Rouge

74104

Tulsa Clinical Research, Tulsa

85004

Xenoscience, Inc., Phoenix

85013

Barrow Neurological Institute, Phoenix

85351

Banner Sun Health Research Institute, Sun City

89106

Cleveland Clinic Lou Ruvo Center, Las Vegas

90033

University of Southern California, Los Angeles

91105

SC3 Research Group - Pasadena, Pasadena

92037

University of California, San Diego, La Jolla

92835

Neurology Center of North Orange County, Fullerton

97239

Oregon Health and Science University, Portland

98108

University of Washington, Seattle

06518

Geriatric and Adult Psychiatry, Hamden

06510

Yale University School of Medicine, New Haven

06905

Ki Health PARTNERS LLC DBA NEW ENGLAND INSTITUTE FOR CLINICAL RESEARCH, Stamford

04401

Northern Light Acadia Hospital, Bangor

08540

Princeton Medical Institute, Princeton

02903

Rhode Island Hospital, Providence

78229-3900

The Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases,University of Texas Health Science Center at San Antonio, San Antonio

Sponsors
All Listed Sponsors
collaborator

Alzheimer's Disease Cooperative Study (ADCS)

OTHER

lead

Biohaven Pharmaceuticals, Inc.

INDUSTRY