Study of Oral Mifepristone as Salvage Therapy in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer

PHASE2TerminatedINTERVENTIONAL
Enrollment

3

Participants

Timeline

Start Date

December 31, 2015

Primary Completion Date

October 15, 2020

Study Completion Date

October 15, 2020

Conditions
Non-Small Cell Lung Cancer (NSCLC)
Interventions
DRUG

Mifepristone

Mifepristone is an antagonist of the GR-II (glucocorticoid) receptor, yet has little affinity for the GR-I (mineralocorticoid) receptor. Mifepristone is also a potent antagonist at the progesterone receptor, and may block the androgen receptor to a limited degree.

Trial Locations (1)

19027

Cooper Institute for Reproductive Hormonal Disorders, Melrose Park

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Corcept Therapeutics

INDUSTRY

lead

Check, Jerome H., M.D., Ph.D.

INDIV