Oral Ponesimod Versus Teriflunomide In Relapsing MUltiple Sclerosis

PHASE3CompletedINTERVENTIONAL
Enrollment

1,133

Participants

Timeline

Start Date

June 4, 2015

Primary Completion Date

May 16, 2019

Study Completion Date

May 16, 2019

Conditions
Multiple Sclerosis
Interventions
DRUG

ponesimod

film-coated tablet with 20 mg ponesimod, administered orally once daily in the morning

DRUG

teriflunomide

film-coated tablet with 14 mg teriflunomide, administered orally once daily in the morning

Trial Locations (162)

1015

Investigator Site 3401, Riga

1113

Investigator Site 2711, Sofia

1145

Investigator Site 2903, Budapest

1204

Investigator Site 2905, Budapest

1309

Investigator Site 2702, Sofia

1407

Investigator Site 2707, Sofia

1431

Investigator Site 2701, Sofia

Investigator Site 2708, Sofia

1606

Investigator Site 2703, Sofia

2143

Investigator Site 2909, Kistarcsa

2500

Investigator Site 2910, Esztergom

4002

Investigator Site 2709, Plovdiv

9023

Investigator Site 2902, Győr

10000

Investigator Site 2502, Zagreb

Investigator Site 2508, Zagreb

Investigator Site 2509, Zagreb

10008

Investigator Site 3725, Zhytomyr

11000

Investigator Site 2601, Belgrade

Investigator Site 2606, Belgrade

11080

Investigator Site 2607, Belgrade

11521

Investigator Site 1303, Athens

11525

Investigator Site 1301, Athens

13100

Investigator Site 4010, Zfat

14001

Investigator Site 3714, Chernihiv

14029

Investigator Site 3701, Chernihiv

15125

Investigator Site 1307, Athens

16132

Investigator Site 1409, Genova

18000

Investigator Site 2602, Niš

20520

Investigator Site 2202, Turku

21005

Investigator Site 3718, Vinnytsia

27607

Investigator Site 8040, Raleigh

28006

Investigator Site 1502, Madrid

29010

Investigator Site 1501, Málaga

31000

Investigator Site 2506, Osijek

31203

Investigator Site 7410, Chihuahua City

32174

Investigator Site 8065, Ormond Beach

33076

Investigator Site 1713, Bordeaux

33100

Investigator Site 2212, Tampere

33612

Investigator Site 8018, Tampa

34000

Investigator Site 2603, Kragujevac

36011

Investigator Site 3717, Poltava

37064

Investigator Site 8015, Franklin

41009

Investigator Site 1506, Seville

43214

Investigator Site 8006, Columbus

44093

Investigator Site 1715, Nantes

46027

Investigator Site 3730, Ternopil

46256

Investigator Site 8013, Indianapolis

50161

Investigator Site 3502, Kaunas

55131

Investigator Site 1104, Mainz

61080

Investigator Site 9004, Trabzon

61103

Investigator Site 3723, Kharkiv

61176

Investigator Site 3724, Kharkiv

63003

Investigator Site 1703, Clermont-Ferrand

64710

Investigator Site 7409, Monterrey

65009

Investigator Site 3703, Odesa

67091

Investigator Site 1705, Strasbourg

67100

Investigator Site 1413, L’Aquila

69000

Investigator Site 3722, Zaporizhia

71000

Investigator Site 9104, Sarajevo

76008

Investigator Site 3713, Ivano-Frankivsk

76018

Investigator Site 3711, Ivano-Frankivsk

76231

Investigator Site 3504, Šiauliai

79000

Investigator Site 3715, Lviv

79010

Investigator Site 3721, Lviv

80209

Investigator Site 8036, Denver

84058

Investigator Site 8042, Orem

89081

Investigator Site 1102, Ulm

90015

Investigator Site 1403, Cefalù

91767

Investigator Site 8311, Pomona

92011

Investigator Site 8045, Carlsbad

92288

Investigator Site 3503, Klaipėda

99089

Investigator Site 1107, Erfurt

119049

Investigator Site 3831, Moscow

127015

Investigator Site 3803, Moscow

Investigator Site 3840, Moscow

129128

Investigator Site 3810, Moscow

150030

Investigator Site 3842, Yaroslavl

170026

Investigator Site 3819, Tver'

173008

Investigator Site 3835, Veliky Novgorod

194354

Investigator Site 3808, Saint Petersburg

197022

Investigator Site 3833, Saint Petersburg

197110

Investigator Site 3813, Saint Petersburg

197376

Investigator Site 3807, Saint Petersburg

197706

Investigator Site 3815, Saint Petersburg

210023

Investigator Site 3606, Vitebsk

210037

Investigator Site 3604, Vitebsk

214019

Investigator Site 3825, Smolensk

220026

Investigator Site 3603, Minsk

220114

Investigator Site 3602, Minsk

230017

Investigator Site 3605, Grodno

241033

Investigator Site 3837, Bryansk

300723

Investigator Site 2802, Timișoara

305007

Investigator Site 3823, Kursk

308007

Investigator Site 3818, Belgorod

357538

Investigator Site 3812, Pyatigorsk

420029

Investigator Site 3811, Kazan'

443095

Investigator Site 3805, Samara

603076

Investigator Site 3834, Nizhny Novgorod

603155

Investigator Site 3802, Nizhny Novgorod

614990

Investigator Site 3839, Perm

620102

Investigator Site 3836, Yekaterinburg

630007

Investigator Site 3829, Novosibirsk

634050

Investigator Site 3801, Tomsk

650066

Investigator Site 3822, Kemerovo

656024

Investigator Site 3821, Barnaul

660037

Investigator Site 3814, Krasnoyarsk

3109601

Investigator Site 4004, Haifa

7830604

Investigator Site 4005, Ashkelon

9112001

Investigator Site 4006, Jerusalem

T6G 1Z1

Investigator Site 8102, Edmonton

V8R 1J8

Investigator Site 8120, Victoria

K1H 8L6

Investigator Site 8101, Ottawa

J4V 2J2

Investigator Site 8113, Greenfield Park

625 00

Investigator Site 3009, Brno

656 91

Investigator Site 3003, Brno

500 05

Investigator Site 3010, Hradec Králové

586 33

Investigator Site 3006, Jihlava

708 52

Investigator Site 3002, Ostrava-Poruba

532 03

Investigator Site 3007, Pardubice

128 08

Investigator Site 3001, Prague

150 06

Investigator Site 3008, Prague

415 29

Investigator Site 3004, Teplice

06002

Investigator Site 1706, Nice

0112

Investigator Site 3905, Tbilisi

0160

Investigator Site 3904, Tbilisi

0179

Investigator Site 3903, Tbilisi

Investigator Site 3906, Tbilisi

0194

Investigator Site 3902, Tbilisi

01307

Investigator Site 1113, Dresden

04107

Investigator Site 1109, Leipzig

00189

Investigator Site 1405, Roma

LV-1002

Investigator Site 3402, Riga

LV-1038

Investigator Site 3403, Riga

15-270

Investigator Site 3219, Bialystok

85-795

Investigator Site 3215, Bydgoszcz

80-803

Investigator Site 3208, Gdansk

40-595

Investigator Site 3217, Katowice

40-752

Investigator Site 3203, Katowice

05-510

Investigator Site 3205, Konstancin-Jeziorna

95-054

Investigator Site 3216, Ksawerów

20-015

Investigator Site 3220, Lublin

60-355

Investigator Site 3202, Poznan

60-848

Investigator Site 3214, Poznan

61-853

Investigator Site 3207, Poznan

51-685

Investigator Site 3213, Wroclaw

2720 276

Investigator Site 1602, Amadora

4710-243

Investigator Site 1605, Braga

3000-075

Investigator Site 1603, Coimbra

4099-001

Investigator Site 1604, Porto

010825

Investigator Site 2807, Bucharest

022903

Investigator Site 2811, Bucharest

050098

Investigator Site 2804, Bucharest

08003

Investigator Site 1509, Barcelona

08035

Investigator Site 1505, Barcelona

08036

Investigator Site 1504, Barcelona

413 45

Investigator Site 2103, Gothenburg

141 86

Investigator Site 2110, Stockholm

171 76

Investigator Site 2101, Stockholm

03115

Investigator Site 3716, Kyiv

G51 4TF

Investigator Site 2015, Glasgow

PR2 9HT

Investigator Site 2021, Lancashire

M6 8HD

Investigator Site 2003, Salford

Sponsors

Lead Sponsor

All Listed Sponsors
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INDUSTRY

NCT02425644 - Oral Ponesimod Versus Teriflunomide In Relapsing MUltiple Sclerosis | Biotech Hunter | Biotech Hunter