Effect of the Molecular Weight of Oat β-glucan on Its Ability to Lower Serum Cholesterol

PHASE2CompletedINTERVENTIONAL
Enrollment

367

Participants

Timeline

Start Date

November 30, 2008

Primary Completion Date

July 31, 2009

Study Completion Date

August 31, 2009

Conditions
Hypercholesterolemia
Interventions
DIETARY_SUPPLEMENT

Wheat bran

21g per day of ready to eat breakfast cereal containing wheat bran with 8g of total dietary fiber and 0.5g beta-glucan.

DIETARY_SUPPLEMENT

3g high MW

20.2 grams per day of ready to eat cereal containing 6g total dietary fiber and 3g oat beta glucan with high molecular weight

DIETARY_SUPPLEMENT

4g medium MW

28.5g ready to eat cereal containing 8g total dietary fiber and 4g oat beta glucan with medium molecular weight

DIETARY_SUPPLEMENT

3g medium MW

21.1g of ready to eat cereal containing 6g total fiber and 3g oat beta glucan with a medium molecular weight

DIETARY_SUPPLEMENT

4g low MW

28.7g ready to eat cereal containing 8g total dietary fiber and 4g oat beta glucan with low molecular weight

Trial Locations (5)

2006

SUGiRS Human Nutrition Unit, School of Molecular & Microbial Biosciences, Unviersity of Sydney, Sydney

N1G 2W1

Human Nutraceutical Research Unit, Department of Human Health and Nutritional Sciences, University of Guelph, Guelph

M5C 2X3

Glycemic Index Laboratories, Inc., Toronto

Unknown

Nutraceuticals and Functional Foods Institute, Faculte des science de l'agriculture et de l'alimentation, Universite Laval, Laval

RG6 6LA

Reading Scientific Services, Ltd (RSSL), Reading

All Listed Sponsors
collaborator

CreaNutrition, AG

UNKNOWN

collaborator

University of Guelph

OTHER

collaborator

University of Sydney

OTHER

collaborator

Laval University

OTHER

collaborator

Reading Scientific Services Ltd.

INDUSTRY

collaborator

University of Toronto

OTHER

collaborator

Agriculture and Agri-Food Canada

OTHER_GOV

lead

Glycemic Index Laboratories, Inc

INDUSTRY

NCT00981981 - Effect of the Molecular Weight of Oat β-glucan on Its Ability to Lower Serum Cholesterol | Biotech Hunter | Biotech Hunter