100
Participants
Start Date
March 31, 2007
Primary Completion Date
May 31, 2010
Study Completion Date
August 31, 2010
Bosentan
Oral bosentan 62.5 mg BID first 4 weeks followed by 24 weeks of 125 mg BID if the 62.5 mg BID dose was well tolerated
Sildenafil
Oral sildenafil 20 mg TID in patients who do not reach the 6-MWT distance threshold at Week 16
Lead Sponsor
Actelion
INDUSTRY