Orphan Diseases, Decoy Oligonucleotides
Total Trials
29
As Lead Sponsor
25
As Collaborator
4
Total Enrollment
3,807
NCT00548561
Efficacy of TopotectTM (Dexrazoxane) for Accidental Extravasation of Anthracyclines
Phase: Phase 2/3
Role: Lead Sponsor
Start: Jun 30, 2001
Completion: Jul 31, 2003
NCT00548704
A Clinical Trial on Topotect® (Dexrazoxane) in the Treatment of Accidental Extravasation of Anthracyclines
Start: Apr 30, 2002
Completion: Aug 31, 2005
NCT00131261
Clinical Trial of PXD101 in Patients With Advanced Multiple Myeloma
Phase: Phase 2
Start: Jan 31, 2005
Completion: Jun 30, 2007
NCT00421889
A Study of Belinostat + Carboplatin or Paclitaxel or Both in Patients With Ovarian Cancer in Need of Relapse Treatment
Phase: Phase 1/2
Start: Aug 31, 2005
Completion: Feb 28, 2009
NCT00413322
Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors
Phase: Phase 1
Start: Sep 30, 2005
Completion: Jun 30, 2008
NCT00274651
A Phase II Clinical Trial of PXD101 in Patients With Recurrent or Refractory Cutaneous and Peripheral T-Cell Lymphomas
Start: Jan 31, 2006
Completion: Jul 31, 2009
NCT00413075
Study of Oral PXD101 in Patients With Advanced Solid Tumors or Lymphoma
Start: Jun 30, 2006
Completion: Aug 31, 2011
NCT00390780
Efficacy and Safety Study of Miconazole Lauriad to Treat Oropharyngeal Candidiasis in HIV Patients
Phase: Phase 3
Start: Jul 31, 2006
Completion: Jan 31, 2008
NCT00432107
A Study to Assess APO866 for the Treatment of Advanced Melanoma
Completion: Mar 31, 2009
NCT00878800
A Phase I/II Clinical Trial of PXD101 in Combination With Doxorubicin in Patients With Soft Tissue Sarcomas
Start: Dec 31, 2006
Completion: Oct 31, 2012
NCT00431912
A Study of APO866 for the Treatment of Cutaneous T-cell Lymphoma
Start: Feb 28, 2007
Completion: Sep 30, 2011
NCT00435084
A Phase I/II Study to Assess the Safety and Tolerability of APO866 for the Treatment of Refractory B-CLL
Completion: Apr 30, 2009
NCT00437736
A Phase I Dose Finding Study of APO010 in Patients With Solid Tumors
Completion: May 31, 2009
NCT00431340
A Phase II Study of Belinostat in Combination With Bortezomib in Patients With Relapsed, Refractory Multiple Myeloma
Start: Mar 31, 2007
NCT00769314
Phase 3 Clinical Study for the Treatment of Cold Sore
Start: May 31, 2007
Completion: Aug 31, 2009
NCT00878722
Trial of PXD101 (Belinostat) in Combination With Idarubicin to Treat AML Not Suitable for Standard Intensive Therapy
Start: Aug 31, 2007
Completion: Apr 30, 2012
NCT00865969
Belinostat in Relapsed or Refractory Peripheral T-Cell Lymphoma
Role: Collaborator
Start: Dec 15, 2008
Completion: Oct 27, 2014
NCT00873119
Belinostat, Carboplatin and Paclitaxel (BelCaP) Compared to Carboplatin and Paclitaxel in Patients With Cancer of Unknown Primary
Start: Feb 28, 2009
Completion: Dec 31, 2012
NCT01385748
Efficacy and Safety Study of Clonidine Lauriad® to Treat Oral Mucositis
Start: Apr 30, 2010
Completion: Dec 31, 2014
NCT01045915
Safety and Efficacy Study of Electrotransfer of Plasmid AMEP to Treat Advanced or Metastatic Melanoma
Start: Jul 31, 2010
Completion: Jan 31, 2013
NCT01188707
A Trial of Belinostat in Combination With Erlotinib in Patients With Non-small Cell Lung Cancer
Start: Oct 1, 2010
Completion: Jun 30, 2011
NCT01310244
MTD Study PXD-101 in Combination With Paclitaxel + Carboplatin in Chemotherapy-Naive Patients With Stage IV NSCLC
Start: Dec 31, 2010
Completion: Aug 31, 2015
NCT01317927
A Study of Belinostat in Combination With Warfarin in Patients With Solid Tumors or Hematological Malignancies
Completion: Jun 30, 2015
NCT01655693
Efficacy and Safety Doxorubicin Transdrug Study in Patients Suffering From Advanced Hepatocellular Carcinoma
Start: Jun 30, 2012
Completion: May 31, 2019
NCT01764009
Safety and Efficacy of Intramuscular Electrotransfer of Plasmid AMEP in Patients Suffering From Advanced or Metastatic Melanoma
Completion: Mar 31, 2014
NCT02548806
Phase 1 PK, Bioavailability, Safety Study of Clonidine MBT w Catapres in Healthy Volunteers
Start: Sep 30, 2015
Completion: Apr 30, 2016
NCT03579628
AsiDNA (a DNA Repair Inhibitor) Administered IntraVenously in Advanced Solid Tumors
Start: Apr 5, 2018
Completion: Feb 20, 2022
NCT05700669
Study to Assess Safety and Efficacy of AsiDNA in Combination with Olaparib in Participants with Recurrent Solid Tumors
Start: Feb 20, 2023
Completion: Oct 31, 2023
NCT06257758
A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors
Start: Jan 10, 2024
Completion: Jan 1, 2025
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