A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

January 10, 2024

Primary Completion Date

January 1, 2025

Study Completion Date

January 1, 2025

Conditions
Advanced or Metastatic Solid TumorsBreast CancerRecurrent Ovarian CancerProstate Cancer
Interventions
DRUG

VIO-01

"VIO-01 will be administered via intravenous infusion over a 60-minute period once weekly. Dosing will be according to body surface area. Based on emerging PK and PD data, alternative dosing schedules may be investigated during the Phase 1 part of the trial. If an alternative schedule is evaluated, the dose and schedule may not exceed the total dose already tested and cleared during the dose escalation.~In Phase 2, participants will receive VIO-01 by intravenous infusion at RP2D and schedule determined during the phase 1 part of the study."

Trial Locations (3)

32746

Florida Cancer Specialists & Research Institute, Lake Mary

73104

Stephenson Cancer Center - University of Oklahoma, Oklahoma City

78229

Next Oncology, San Antonio

Sponsors
All Listed Sponsors
lead

Valerio Therapeutics

INDUSTRY

NCT06257758 - A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors | Biotech Hunter | Biotech Hunter