Cancer Treatments
Total Trials
31
As Lead Sponsor
10
As Collaborator
21
Total Enrollment
4,282
NCT00867750
SIR-Spheres® Microspheres Versus Transarterial Chemoembolisation in Patients With Unresectable Hepatocellular Carcinoma
Phase: Phase 2
Role: Lead Sponsor
Start: Mar 31, 2006
Completion: Jun 30, 2011
NCT00604409
Study of Capecitabine in Combination With SIR-Spheres in Patients With Advanced Cancer
Phase: Phase 1
Role: Collaborator
Start: Apr 30, 2006
Completion: Jan 31, 2015
NCT00724503
FOLFOX Plus SIR-SPHERES MICROSPHERES Versus FOLFOX Alone in Patients With Liver Mets From Primary Colorectal Cancer
Phase: N/A
Start: Aug 31, 2006
Completion: May 31, 2015
NCT00503867
SIR-Spheres® for the Treatment of Unresectable Hepatocellular Carcinoma
Start: Jul 18, 2007
Completion: Mar 9, 2010
NCT00712790
Study of SIR-Spheres Plus Sorafenib as 1st Line Treatment for Non-resectable Primary Hepatocellular Carcinoma (HCC)
Phase: Phase 1/2
Start: Jun 30, 2008
Completion: Apr 30, 2014
NCT00735241
FOLFOX6 Plus Sir-Spheres Microspheres Plus Avastin in Patients With Nonresectable Liver Metastases From Colorectal Carcinoma
Phase: Phase 2/3
Start: Jul 31, 2008
Completion: Mar 31, 2009
NCT00994370
Measurement of Pro-angiogenic Markers in Patients With Hepatic Metastases Undergoing SIRT
Start: Apr 30, 2009
Completion: Jan 31, 2013
NCT01149304
Preventive Effect of Enoxaparin, Pentoxifylline and Ursodeoxycholic Acid to Radiation Induced Liver Toxicity
Start: Jun 30, 2009
Completion: Not specified
NCT00972036
Selective Internal Radiation Therapy (SIRT) in Patients With Unresectable Colorectal Cancer Liver Metastases Who Failed Prior Intraarterial Pump Chemotherapy
Start: Aug 31, 2009
Completion: Dec 31, 2014
NCT00766220
Yttrium Microspheres With Cetuximab Plus Irinotecan for Patients With Advanced Colorectal Cancer Mets to Liver
Start: Oct 31, 2009
Completion: Jan 31, 2012
NCT01098422
A Study of Yttrium-90 Radioactive Resin Microspheres to Treat Colorectal Adenocarcinoma Metastatic to the Liver
Start: Jan 31, 2010
Completion: Feb 28, 2015
NCT01135056
Study to Compare Selective Internal Radiation Therapy (SIRT) Versus Sorafenib in Locally Advanced Hepatocellular Carcinoma (HCC)
Phase: Phase 3
Start: Jul 31, 2010
Completion: Jul 31, 2018
NCT01186263
Predictive Value of 99mTc- Albumin Spheres Before 90Y- SIR Therapy
Completion: Aug 31, 2013
NCT01126645
Sorafenib and Micro-therapy Guided by Primovist Enhanced MRI in Patients With Inoperable Liver Cancer
Start: Dec 31, 2010
Completion: Dec 31, 2018
NCT01815879
Metastatic Colorectal Cancer Liver Metastases Outcomes After Resin 90Y Microsphere Radioembolization in the USA Evaluation Project
Start: Dec 31, 2012
NCT01721954
FOLFOX6m Plus SIR-Spheres Microspheres vs FOLFOX6m Alone in Patients With Liver Mets From Primary Colorectal Cancer
Start: May 1, 2013
Completion: Feb 28, 2017
NCT02195011
Safety Study of Regorafenib and SIR-Spheres® Microspheres Radioembolization in Patients With Refractory Metastatic Colorectal Cancer With Liver Metastases
Start: Jul 31, 2014
Completion: Jun 4, 2017
NCT02416466
CAR-T Hepatic Artery Infusions and Sir-Spheres for Liver Metastases
Start: Apr 30, 2015
Completion: Jun 30, 2018
NCT02602327
Tas-102 and Radioembolization With 90Y Resin Microspheres for Chemo-refractory Colorectal Liver Metastases
Start: Jan 9, 2017
Completion: Aug 31, 2021
NCT02807181
SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma
Start: Feb 14, 2017
Completion: Apr 29, 2021
NCT03380130
A Study of the Safety and Antitumoral Efficacy of Nivolumab After SIRT for the Treatment of Patients With HCC
Start: Sep 11, 2017
Completion: Nov 4, 2020
NCT04736121
Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients
Start: May 28, 2021
Completion: Dec 31, 2026
NCT05315687
Radioembolization of Metastatic Breast Cancer to the Liver as a 2nd/3rd Line Therapy
Start: Aug 17, 2022
Completion: Jul 31, 2025
NCT05377034
Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients
Start: Oct 26, 2022
Completion: Jan 31, 2028
NCT05195710
Preoperative Y-90 Radioembolization for Tumor Control and Future Liver Remnant Hypertrophy in Patients With Colorectal Liver Metastases
Start: Nov 16, 2022
Completion: Mar 31, 2026
NCT05701488
SIRT With Tremelimumab and Durvalumab for Resectable HCC
Start: Apr 21, 2023
Completion: Oct 1, 2026
NCT05848947
SIR-Spheres Study to Calculate the Radiation-Absorbed Dose of 99mTc-MAA
Phase: Phase 4
Start: Apr 25, 2023
Completion: Jul 5, 2023
NCT05967143
Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry)
Start: Jun 19, 2023
Completion: Jun 30, 2029
NCT06035952
Study of 3D Scanning for Adolescent Scoliosis
Start: Aug 7, 2023
Completion: Dec 15, 2023
NCT05655949
Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio
Start: Feb 13, 2024
Completion: Dec 1, 2027
NCT06555133
Y-90, Capecitabine, and Atezolizumab for Oligometastatic CRC
Start: Apr 7, 2025
Completion: Sep 1, 2029
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