Defunct Company
Total Trials
16
As Lead Sponsor
11
As Collaborator
5
Total Enrollment
2,038
NCT03452397
Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study)
Phase: Phase 2
Role: Lead Sponsor
Start: Feb 27, 2018
Completion: Apr 27, 2018
NCT03633461
Evaluation of the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (the RAINIER Study)
Start: Aug 14, 2018
Completion: Sep 20, 2018
NCT03636061
Evaluation of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease
Start: Aug 15, 2018
Completion: Sep 26, 2018
NCT03920215
Evaluation of the Long Term Follow up of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease
Phase: Phase 2/3
Completion: Sep 20, 2019
NCT03688802
Efficacy of OC-01 Nasal Spray on Goblet Cell and Meibomian Gland Stimulation
Start: Sep 25, 2018
Completion: Sep 30, 2019
NCT03873246
Clinical Trial to Evaluate the Chronic Efficacy of OC-01 Nasal Spray on Signs of Dry Eye Disease (The MYSTIC Study)
Start: Feb 18, 2019
Completion: Jan 7, 2020
NCT04036292
Evaluation of the Efficacy and Safety of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease
Phase: Phase 3
Start: Jul 23, 2019
Completion: Feb 5, 2021
NCT04072146
Evaluating Relative Bioavailability of OC-01 (Varenicline) Nasal Spray as Compared to Orally Administered Varenicline
Phase: Phase 1
Start: Aug 26, 2019
Completion: Nov 15, 2019
NCT04957758
Phase 2 Clinical Trial to Evaluate OC-01 Nasal Spray in Subjects With Neurotrophic Keratopathy
Start: Jun 17, 2021
Completion: Apr 28, 2023
NCT05566717
An Investigator-Initiated Study to Assess the Association of Diabetic Retinopathy Severity Scale (DRSS) With Level of Decreased Corneal Sensitivity
Phase: N/A
Role: Collaborator
Start: Jul 1, 2022
Completion: Oct 31, 2022
NCT05378945
Clinical Trial to Evaluate the Efficacy and Safety of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease
Start: Jul 22, 2022
Completion: Apr 4, 2023
NCT05486468
The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment
Start: Oct 5, 2022
Completion: Dec 31, 2026
NCT05576415
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of OC-01 in Adult Chinese With Dry Eye Disease
Start: Dec 7, 2022
Completion: Apr 27, 2023
NCT05700422
Nasal Spray Study in Sjogren's Dry Eye Disease
Phase: Phase 4
Start: May 1, 2023
Completion: Aug 31, 2023
NCT05918406
Phase 4 Study Evaluating the Safety of the Nasal Guide With Tyrvaya
Start: Jun 14, 2023
Completion: Aug 18, 2023
NCT06329687
A Study Evaluating the Safety of the Nasal Pump
Start: Feb 21, 2024
Completion: Feb 28, 2024