Small Molecules
Total Trials
21
As Lead Sponsor
17
As Collaborator
4
Total Enrollment
1,532
NCT00295854
Phase II Study Efficacy and Safety of Two Dosing Regimens of MN-001 in Patients With Interstitial Cystitis
Phase: Phase 2
Role: Lead Sponsor
Start: May 31, 2005
Completion: Oct 31, 2006
NCT00679263
Study Evaluating the Safety and Effects of MN-221 in Subjects With Moderate to Severe Asthma
Start: Feb 29, 2008
Completion: Jul 31, 2008
NCT00683449
Study Evaluating the Safety and Effects of MN-221 in Subjects Experiencing an Acute Exacerbation of Asthma
Start: Jun 30, 2008
Completion: Mar 31, 2009
NCT00838591
Study Evaluating the Safety and Efficacy of MN-221 as an Adjunct to Standard Therapy in Subjects Experiencing an Acute Exacerbation of Asthma
Start: Mar 31, 2009
Completion: Mar 31, 2012
NCT01013142
Evaluate the Safety of MN-221 in Subjects With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Phase: Phase 1
Start: Nov 30, 2009
Completion: Mar 31, 2010
NCT01217970
Safety Interaction Trial Ibudilast and Methamphetamine
Role: Collaborator
Start: Jan 31, 2011
Completion: Mar 31, 2013
NCT01551316
Safety Study to Evaluate MN-221 in Chronic Obstructive Pulmonary Disease (COPD) Patients
Start: Mar 31, 2012
Completion: May 31, 2012
NCT01740414
Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers
Start: Nov 30, 2012
Completion: May 31, 2017
NCT01982942
Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis
Start: Nov 30, 2013
Completion: Dec 31, 2017
NCT02238626
Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Start: Sep 30, 2014
NCT02503657
Safety, Tolerability, and Efficacy of MN-001 (Tipelukast) in Patients With Idiopathic Pulmonary Fibrosis
Start: Mar 9, 2016
Completion: Mar 15, 2022
NCT02681055
Open-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD Subjects
Start: Mar 31, 2016
Completion: Oct 1, 2019
NCT02714036
A Biomarker Study to Evaluate MN-166 in Subjects With Amyotrophic Literal Sclerosis (ALS)
Phase: Phase 1/2
Start: May 6, 2016
Completion: Jun 30, 2020
NCT03533387
Study of MN-166 (Ibudilast) Extended Release Tablet Formulations Compared With Capsules in Healthy Volunteers
Start: Apr 11, 2018
Completion: Sep 30, 2018
NCT03594435
Ibudilast for the Treatment of Alcohol Use Disorder
Start: Oct 1, 2018
Completion: Apr 19, 2023
NCT03782415
Study to Evaluate Ibudilast and TMZ Combo Treatment in Newly Diagnosed and Recurrent Glioblastoma
Start: Dec 29, 2018
Completion: Aug 7, 2023
NCT04054206
Relative Bioavailability of MN-166 (Ibudilast) in Extended Release Tablet vs. Intermediate-release Capsule in Healthy Volunteers
Start: Jun 24, 2019
Completion: May 31, 2020
NCT04057898
Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS
Phase: Phase 2/3
Start: May 28, 2020
Completion: Dec 31, 2026
NCT04429555
Efficacy, Safety, Tolerability, and Biomarkers of Ibudilast (MN-166) in Patients Hospitalized With COVID-19 at Risk for ARDS
Start: Jan 11, 2021
Completion: Aug 7, 2024
NCT05464784
MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia
Start: Aug 22, 2022
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