Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers

PHASE2CompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

November 30, 2012

Primary Completion Date

December 31, 2015

Study Completion Date

May 31, 2017

Conditions
Opioid AbuseOpioid Dependence
Interventions
DRUG

MN-166 (50 mg) First

In this arm of the study participants were first maintained on 50 mg MN-166 BID for approximately 14 days, and were then switched onto placebo maintenance. The subjective and analgesic effects of Oxycodone (0 mg, 15 mg and 30 mg) were tested under each of the two maintenance conditions (Placebo \& MN-166).

DRUG

Placebo First

This arm of the study participants were first maintained on placebo for approximately 14 days, and were then switched onto 50mg MN-166 BID maintenance. . The subjective and analgesic effects of Oxycodone (0 mg, 15 mg and 30 mg) were tested under each of the two maintenance conditions (Placebo \& MN-166).

Trial Locations (1)

10032

New York State Psychiatric Institute, New York

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

collaborator

MediciNova

INDUSTRY

lead

New York State Psychiatric Institute

OTHER