Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS

PHASE2/PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

234

Participants

Timeline

Start Date

May 28, 2020

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
Amyotrophic Lateral Sclerosis
Interventions
DRUG

MN-166

Subjects will take MN-166 for 12 months followed by a 6-month open-label extension phase.

DRUG

placebo

Subjects will take matching placebo for 12 months followed by a 6-month open-label extension phase.

Trial Locations (16)

13210

SUNY Upstate Medical University, Syracuse

18103

Lehigh Valley Health Network, Allentown

21287

Johns Hopkins University, Baltimore

22908

University of Virginia Health System, Charlottesville

27705

Duke University, Durham

30912

Augusta University, Augusta

32224

Mayo Clinic, Jacksonville

46202

Indiana University IU Health Neuroscience Center, Indianapolis

55415

Hennepin Healthcare Research Institute, Minneapolis

92868

University of California, Orange

T6G 2G3

University of Alberta Hospital, Edmonton

L8N 3Z5

McMaster University Medical Center, Hamilton

M4N 3M5

Sunnybrook Research Institute, Toronto

H3A 2B4

Montreal Neurological Institute and Hospital, Montreal

S7K 0M7

University of Saskatchewan - Sastakoon Hospital, Saskatoon

G1J 1Z4

Hopital de L'Enfant-Jesus, CHU de Quebec-Universite Laval, Québec

Sponsors

Lead Sponsor

All Listed Sponsors
lead

MediciNova

INDUSTRY