About
siRNA Therapies
Areas of Focus
Categories
Gene Therapy, RNA & Peptide Therapy
Clinical Trials (6)
View allTotal Trials
6
As Lead Sponsor
5
As Collaborator
1
Total Enrollment
42,229
By Phase
PHASE2: 1PHASE2/PHASE3: 2PHASE1/PHASE2: 2
By Status
RECRUITING: 4ACTIVE_NOT_RECRUITING: 1COMPLETED: 1
Clinical Trials Pipeline6 trials
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Phase 1/2
Phase 2/3
N/A
2009
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2025
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2028
2029
Today
Hover over trial bars to see details
Recent Trials
NCT07205887Lead Sponsor
A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO
PHASE2Recruiting
160 participants
Started: Sep 12, 2025 · Completed: Jun 30, 2028
NCT06957080Lead Sponsor
A Study of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME
PHASE2/PHASE3Recruiting
960 participants
Started: Apr 16, 2025 · Completed: Jun 30, 2028
NCT06664502Lead Sponsor
A 2-part Study Consisting of a Multiple Ascending Dose Safety Study in Participants With Macular Edema Following Branch Retinal Vein Occlusion and a Dose-finding Safety and Preliminary Efficacy Study in Participants With Either Diabetic Macular Edema or Neovascular Age-related Macular Degeneration
PHASE1/PHASE2Recruiting
92 participants
Started: Nov 12, 2024 · Completed: May 31, 2026
NCT06571045Lead Sponsor
A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME
PHASE2/PHASE3Active, not recruiting
984 participants
Started: Aug 7, 2024 · Completed: Dec 31, 2027
NCT05919693Lead Sponsor
A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD)
PHASE1/PHASE2Completed
33 participants
Started: Jun 12, 2023 · Completed: Aug 26, 2024
Locations (1)
Headquarters
L'Aquilo, Italy
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