Clinical-stage oncology company with a lead program in US-based phase II trials for brain cancer
Total Trials
13
As Lead Sponsor
5
As Collaborator
8
Total Enrollment
1,837
NCT00022295
Phenoxodiol in Treating Patients With Refractory Solid Tumors
Phase: Phase 1
Role: Lead Sponsor
Start: Aug 31, 2001
Completion: Oct 31, 2007
NCT02903771
Phase I Study of Cantrixil in Patients With Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer.
Start: Dec 5, 2016
Completion: Mar 24, 2020
NCT03522298
Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma
Phase: Phase 2
Start: May 15, 2018
Completion: Mar 30, 2023
NCT03696355
Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas
Role: Collaborator
Start: Nov 19, 2018
Completion: Sep 4, 2022
NCT03765983
GDC-0084 in Combination With Trastuzumab for Patients With HER2-Positive Breast Cancer Brain Metastases
Start: Feb 11, 2019
Completion: Nov 30, 2025
NCT03970447
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
Phase: Phase 2/3
Start: Jul 30, 2019
Completion: Jun 30, 2030
NCT03994796
Genetic Testing in Guiding Treatment for Patients With Brain Metastases
Start: Oct 17, 2019
Completion: Jun 30, 2028
NCT04192981
GDC-0084 With Radiation Therapy for People With PIK3CA-Mutated Solid Tumor Brain Metastases or Leptomeningeal Metastases
Start: Dec 6, 2019
Completion: Dec 31, 2026
NCT04906096
Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL
Start: Jun 1, 2021
Completion: Dec 1, 2027
NCT05012670
Mass Balance Recovery, Metabolite Profile, and Metabolite Identification of [14C]-Paxalisib in Healthy Male Subjects
Start: Aug 18, 2021
Completion: Jan 30, 2024
NCT05114668
Safety, Tolerability, and Pharmacokinetics of EVT801 in Patients With Advanced Solid Tumours
Start: Nov 3, 2021
Completion: Nov 22, 2024
NCT05183204
Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma
Start: Feb 14, 2022
Completion: Dec 31, 2025
NCT06208657
Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer
Phase: Phase 1/2
Start: Jul 10, 2024
Completion: Dec 31, 2035
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