Addiction Treatments
Total Trials
59
As Lead Sponsor
51
As Collaborator
8
Total Enrollment
10,256
NCT00279565
Buprenorphine Versus Methadone Maintenance in Hepatitis C Patients Receiving Peg-Intron and Rebetol (Study P04279)(TERMINATED)
Phase: Phase 4
Role: Lead Sponsor
Start: Aug 31, 2005
Completion: Feb 28, 2007
NCT01075971
Study of Two Formulations of Buprenorphine HCl in Opioid-dependent Subjects on Buprenorphine Maintenance Therapy (Study P04451) (COMPLETED)
Phase: Phase 2
Start: Sep 30, 2005
Completion: Nov 30, 2005
NCT00838396
A Study to Evaluate the Efficacy and Safety of Controlled Release Arbaclofen Placarbil (XP19986) in Patients With Gastroesophageal Reflux Disease
Start: Oct 31, 2005
Completion: Aug 31, 2006
NCT00756353
"Survey of Buprenorphine Use Among Out of Care Population in France (P04933)(COMPLETED)"
Phase: N/A
Start: Jun 30, 2006
Completion: Dec 31, 2006
NCT00723697
Observational Study of Misuse of High Dose Buprenorphine (Subutex® or Generic) in Opiate-Addicted Patients in France (Study P05186AM1)(COMPLETED)
Start: May 31, 2007
Completion: Feb 28, 2010
NCT00684073
Preference for Subutex® (Buprenorphine) Versus Suboxone® (Buprenorphine/Naloxone) in Opioid Dependent Patients on Subutex® (Study P05094)(COMPLETED)
Start: Jul 31, 2007
Completion: Dec 31, 2007
NCT00640835
Safety and Tolerability of Buprenorphine/Naloxone Film Strips
Start: Feb 29, 2008
Completion: Oct 31, 2008
NCT00605033
A Randomized Acceptability and Safety Study of the Transfer From Subutex to Suboxone in Opioid- Dependent Subjects (Study P04843)(COMPLETED)
Start: Mar 31, 2008
Completion: May 31, 2009
NCT00637000
Induction of Opioid-Dependent Individuals Onto Buprenorphine and Buprenorphine/Naloxone
Completion: Sep 30, 2008
NCT00723749
Treatment of Opioid Dependent Patients With Suboxone: Acceptability & Safety Data From Real Life Scenario (Study P05603)
Completion: Dec 31, 2010
NCT00725608
Acceptability and Safety of Switching From Subutex or Other Opioid Drug Dependence Therapy to Suboxone (NIS P05444)
Start: May 31, 2008
Completion: Apr 30, 2011
NCT00679458
Randomized, Double-Blind Cross-Over Trial Of Buprenorphine and Low-Dose Naloxone Versus Buprenorphine
Role: Collaborator
Start: Sep 30, 2008
Completion: Nov 30, 2009
NCT00901875
Multicentre Trial of Suboxone in Opiate-dependent Subjects in Taiwan
Start: Mar 31, 2009
Completion: Jan 31, 2010
NCT01760473
Reinforcing Effects of Intranasal (IN) Buprenorphine Versus Buprenorphine/Naloxone
Phase: Phase 3
Start: May 31, 2009
Completion: Dec 31, 2014
NCT00955162
"Effectiveness of Buprenorphine/Naloxone in Reducing Intravenous Buprenorphine Misuse in France (RIME)"
Start: Aug 31, 2009
Completion: May 31, 2011
NCT02765555
First in Man Study of Safety, Tolerability and PK Profile of RBP-7000
Phase: Phase 1
Start: Mar 31, 2010
Completion: Sep 30, 2010
NCT02765867
Single-dose, Study of RBP-6000 in Opioid Dependent Individuals
Start: Nov 30, 2010
NCT02768649
Single Ascending Dose Study of RBP-7000
Start: Apr 30, 2011
Completion: Feb 29, 2012
NCT01582347
Transfer of Subjects From Subutex/Suboxone to RBP-6300
Start: Mar 31, 2012
Completion: Nov 30, 2012
NCT03002961
Single Ascending Dose Study of RBP-6000
Start: Jul 31, 2012
Completion: Oct 31, 2013
NCT01677377
Multiple Ascending Dose Study of the Safety, Tolerability, Pharmacokinetic/Efficacy
Start: Aug 31, 2012
Completion: Apr 30, 2013
NCT01846455
Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects
Start: Sep 30, 2012
Completion: May 31, 2013
NCT01738503
Multiple Dose Pharmacokinetics Depot Buprenorphine in Opioid-Dependent Subjects
Start: Oct 31, 2012
Completion: May 31, 2014
NCT01846481
A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse
Start: Apr 30, 2013
Completion: Jun 30, 2013
NCT02038790
Usability of Zubsolv Sublingual Tablets 5.7/1.4 to Suboxone Sublingual Film 8/2 In Buprenorphine/Naloxone Treated Opioid Dependent Population
Start: Nov 30, 2013
Completion: Nov 30, 2013
NCT02044094
Multiple Dose Study of Blockade of Opioid Effects by Injections of Buprenorphine in Participants With Opioid Disorder
Completion: Jul 31, 2014
NCT02109562
Randomized, Double-blind, Placebo Controlled, Multi-center and Tolerability of RBP-7000 in Schizophrenia Patients
Start: Apr 30, 2014
Completion: Nov 30, 2014
NCT02136784
Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals
NCT02203838
Long Term Study of RBP 7000 in the Treatment of Subjects With Schizophrenia
Start: Jun 30, 2014
Completion: Sep 30, 2016
NCT02535494
Risks and Benefits of Naloxone Prescribing
Start: Jul 31, 2014
Completion: Dec 31, 2021
NCT02357901
Treatment Seeking Participants With Opioid Use Disorders Assessing Tolerability of Depot Injections of Buprenorphine
Start: Jan 28, 2015
Completion: Apr 29, 2016
NCT02510014
Safety and Tolerability Study of Depot Buprenorphine in Treatment Seeking Subjects With Opioid Use Disorder
Start: Jul 27, 2015
Completion: Jan 31, 2017
NCT03604861
An Observational Study of Environmental and SocioEconomic Factors in Opioid Recovery
Start: Aug 31, 2015
Completion: Mar 31, 2019
NCT02511886
A Dose-Escalation Study to Determine the Maximum Tolerated Dose of Arbaclofen Placarbil in Subjects With Alcohol Use Disorder
Start: Sep 30, 2015
Completion: Jan 31, 2016
NCT02559973
Pharmacokinetics, Safety, and Tolerability of Depot Buprenorphine at Three Different Molecular Weights in Treatment-Seeking Subjects With Opioid Use Disorder
Completion: Mar 31, 2016
NCT02687984
PK, Safety, and Tolerability Study of RBP-7000 of Different Molecular Weight Polymer in Subjects With Schizophrenia
Start: Feb 29, 2016
Completion: May 31, 2016
NCT02896296
Open-Label Treatment Extension Study
Start: Aug 17, 2016
Completion: Aug 23, 2017
NCT03058237
A Phase 1 Bioavailability Study of Arbaclofen Placarbil Modified Release Formulations in Healthy Volunteers
Start: Jan 24, 2017
Completion: Jul 5, 2017
NCT03715634
Study of a Novel Subcutaneous Depot Formulation of Buprenorphine
Start: Sep 20, 2017
Completion: Jun 7, 2018
NCT03747341
Buprenorphine-Fentanyl Interaction Study
Start: Mar 22, 2018
Completion: Jan 4, 2019
NCT03818399
Virginia Opioid Overdose Treatment InitiatVE
Start: Jan 4, 2019
Completion: Feb 24, 2021
NCT03752528
Evaluation of Long-term Buprenorphine Plasma Exposure
Start: Feb 19, 2019
Completion: Jul 18, 2019
NCT03978832
Safety, Tolerability, Pharmacokinetics and Efficacy of 180 mg Subcutaneous Risperidone From 6 mg Oral Risperidone
Start: Jun 28, 2019
Completion: May 12, 2020
NCT03993392
SUBLOCADE Rapid Initiation Study
Start: Aug 29, 2019
Completion: Dec 26, 2019
NCT04060654
SUBLOCADE Rapid Initiation Extension Study
Start: Oct 21, 2019
Completion: May 15, 2020
NCT04413552
INDV-2000 First in Human
Start: Jul 6, 2020
Completion: Apr 13, 2021
NCT04577144
An Observational Study of Environmental and Socioeconomic Factors in Opioid Recovery - Long Term
Start: Sep 20, 2020
Completion: Jan 11, 2021
NCT04523792
Virginia Opioid Treatment-Emergency Department
Start: Jan 1, 2021
NCT05009160
DreaMS - Validation Study 1
Start: Mar 30, 2022
Completion: Mar 31, 2027
NCT04976855
Study to Assess Repeated Doses of INDV-2000 in Healthy Volunteers and in Treatment Seeking Individuals With Opioid Use Disorder
Start: Aug 17, 2022
Completion: Jul 5, 2023
NCT04815590
Extended-release Injectable Buprenorphine for Individuals at High Risk of Overdose
Start: Oct 17, 2022
Completion: Oct 17, 2023
NCT05704543
Evaluation of Buprenorphine Extended-Release Subcutaneous Injection at Alternative Injection Locations
Start: Mar 1, 2023
Completion: Nov 1, 2023
NCT05694533
Study of Potential CYP3A4 Induction by INDV-2000 in Healthy Adults
Start: Mar 16, 2023
Completion: May 1, 2023
NCT05974046
Single Dose Study of [14C]-IDV184001AN ([14C]-IDV184001) in Healthy Adult Male Participants
Start: Jul 10, 2023
Completion: Jul 21, 2023
NCT05860959
SUBLOCADE Long-term Outcomes
Start: Aug 31, 2023
Completion: Aug 31, 2025
NCT05878210
Evaluating the SUBLOCADE Treatment Exit Strategy
Start: Nov 24, 2023
Completion: May 9, 2025
NCT06384157
Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder
Start: Jun 10, 2024
Completion: Dec 31, 2025
NCT06576843
INDV-6001 Multiple-Dose Pharmacokinetic Study
Start: Sep 17, 2024
NCT07174869
A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population
Start: Sep 30, 2025
Completion: Jun 30, 2026
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