A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse

RBP-8000 100 mg administered in the vein on either study day 3 or 6. There is a 72-hour washout between Days 3 and 6

IV infusion of Placebo administered 1 minute after cocaine infusion on either day 3 or 6.

50 mg intravenous (IV) dose of cocaine administered over 10 minutes on Days 1, 3 and 6.

RBP-8000 200 mg administered in the vein on either study day 3 or 6. There is a 72-hour washout between Days 3 and 6