Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

June 10, 2024

Primary Completion Date

November 30, 2025

Study Completion Date

December 31, 2025

Conditions
Opioid Use Disorder
Interventions
DRUG

INDV-2000

INDV-2000 is a highly potent and selective OX1R antagonist that is being developed as a therapy for the treatment of OUD.

OTHER

Placebo

This is a randomized, double-blind, placebo-controlled study.

Trial Locations (35)

10314

Richmond Behavioral Associates, Staten Island

10464

Dr Vando Medical Services, The Bronx

21229

Maryland Treatment Centers, Baltimore

28112

Monroe Biomedical Research, Monroe

28557

West Clinical Research, Morehead City

29605

Prisma Health Addiction Medicine Center, Greenville

30328

Agile Clinical Research Trials, Atlanta

32224

Bold City Clinical Research, Jacksonville

33016

Segal Trials Miami Lakes, Miami Lakes

33060

Clinical Research Center of Florida, Pompano Beach

33140

Quantum Clinical Trials, Miami Beach

33435

Imagine Research of Palm Beach County, Boynton Beach

33803

Accel Research Sites - Lakeland, Lakeland

34741

Vitalix Kissimmee, Kissimmee

35570

Boyett Health Services Inc, Hamilton

39232

Precise Research Centers, Flowood

45417

Midwest Clinical Research Center, LLC, Dayton

48507

Insight Research Institute, Flint

63141

Arch Clinical Trials, St Louis

73112

Pahl Pharmaceutical Professionals, LLC, Oklahoma City

SP Research PLLC Rivus Wellness and Research Insitute, Oklahoma City

73118

Unity Clinical Research, Oklahoma City

75115

Insite Clinical Research, LLC, DeSoto

77043

HD Research, Houston

79902

El Paso Clinical Trials, El Paso

84010

Progressive Clinical Research Llc, Bountiful

84015

Alpine Research Organisation, Clinton

84604

Boeson Clinical Research, Provo

85018

Elite Clinical Studies, LLC, Phoenix

89102

IMA Clinical Research, Las Vegas

89121

Oasis Clinical Research, Las Vegas

91767

Empire Clinical Research, Pomona

92054

North County Clinical Research, Oceanside

92103

Artemis Institute For Clinical Research - San Diego, San Diego

01608

Vitalix Clinical, Worcester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Indivior Inc.

INDUSTRY

NCT06384157 - Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder | Biotech Hunter | Biotech Hunter