Cancer immunotherapy, RNAi
Total Trials
16
As Lead Sponsor
15
As Collaborator
1
Total Enrollment
379
NCT01061840
Trial of Bi-shRNA-furin and GMCSF Augmented Autologous Tumor Cell Vaccine for Advanced Cancer
Phase: Phase 1
Role: Lead Sponsor
Start: Dec 31, 2009
Completion: Jan 31, 2019
NCT01309230
A Trial of FANG™ Vaccine for Participants With Ovarian Cancer
Phase: Phase 2
Start: Mar 8, 2011
Completion: Feb 2, 2022
NCT01453361
Phase II FANG™ in Advanced Melanoma
Start: Oct 31, 2011
Completion: Mar 22, 2016
NCT01505153
Phase I Intratumoral Pbi-shRNA STMN1 LP in Advanced and/or Metastatic Cancer
Start: Feb 29, 2012
Completion: Apr 13, 2017
NCT01505166
Randomized Phase II Adjuvant Chemotherapy ± FANG™ in Colorectal Carcinoma With Liver Metastases
Start: Mar 31, 2012
Completion: Aug 31, 2016
NCT01551745
Salvage Ovarian FANG™ Vaccine + Bevacizumab
Completion: Apr 30, 2016
NCT01867086
Salvage Ovarian FANG™ Vaccine + Carboplatinum
Start: Jun 30, 2013
Completion: Apr 8, 2016
NCT02346747
A Trial of Vigil for Participants With Ovarian Cancer
Start: Feb 28, 2015
Completion: Dec 31, 2025
NCT02574533
Pilot Study of Vigil™ + Pembrolizumab for Advanced Melanoma
Start: Oct 31, 2015
Completion: Sep 30, 2017
NCT02511132
A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcoma
Start: Feb 10, 2016
Completion: Dec 23, 2020
NCT02639234
Vigil™ + Nivolumab in Advanced Non-Small Cell Lung Cancer
Start: Mar 31, 2016
Completion: Mar 31, 2017
NCT02725489
Pilot Study of Durvalumab and Vigil in Advanced Women's Cancers
Role: Collaborator
Start: Jun 3, 2016
Completion: Dec 2, 2020
NCT02736565
Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's Sarcoma
Start: Oct 31, 2016
Completion: Aug 4, 2020
NCT03073525
A Trial of Atezolizumab and Vigil in Patients With Advanced Gynecological Cancers
Start: May 31, 2017
Completion: May 18, 2022
NCT03495921
A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and Temozolomide
Phase: Phase 3
Start: Aug 21, 2018
Completion: Jan 20, 2022
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