Pilot Study of Vigil™ + Pembrolizumab for Advanced Melanoma

PHASE1CompletedINTERVENTIONAL
Enrollment

2

Participants

Timeline

Start Date

October 31, 2015

Primary Completion Date

September 30, 2017

Study Completion Date

September 30, 2017

Conditions
Melanoma RecurrentMalignant MelanomaMelanoma
Interventions
BIOLOGICAL

Vigil

Vigil™ 1 x 10e7 cells via intradermal injection on Day 1, 15, 29, 43 and then every 3 weeks thereafter for a minimum of 4 administrations and a maximum of 9 administrations (depending on the quantity of Vigil™ manufactured from surgical specimens)

DRUG

Pembrolizumab

Pembrolizumab 2mg/kg by intravenous infusion over 30 minute starting on day 43 and every 3 weeks thereafter

Trial Locations (3)

75230

Mary Crowley Medical Research Centers, Dallas

79606

Texas Oncology P.A., Texas Cancer Center, Abilene

99202

Cancer Care Northwest, Spokane

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gradalis, Inc.

INDUSTRY