Vigil™ + Nivolumab in Advanced Non-Small Cell Lung Cancer

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

March 31, 2016

Primary Completion Date

March 31, 2017

Study Completion Date

March 31, 2017

Conditions
Advanced Non-small Cell Lung CancerMetastatic Non-small Cell Lung CancerLung Neoplasms
Interventions
BIOLOGICAL

Vigil™

Upon completion of nivolumab infusion, subjects will receive Vigil™, 1.0 x 10\^7cells via intradermal injection on Day 1 every 14 days for a minimum of 4 and a maximum of 12 doses depending on quantity of Vigil™ manufactured from surgical specimens.

DRUG

Nivolumab

Prior to Vigil™, subjects will receive nivolumab 3 mg/kg by intravenous infusion over 60 minutes on Day 1 every 14 days. If nivolumab is administered beyond 12 months it will be administered off study.

Trial Locations (3)

75230

Mary Crowley Cancer Research Centers, Dallas

79606

Texas Oncology, P.A., Texas Cancer Center, Abilene

99216

Cancer Care Northwest, Spokane Valley

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gradalis, Inc.

INDUSTRY