SIRNA, Biologics, Monoclonal Antibodies, Small Molecules
Total Trials
15
As Lead Sponsor
12
As Collaborator
3
Total Enrollment
7,893
NCT04479631
Safety, Tolerability, and Pharmacokinetics Study of Human Monoclonal Antibody BRII-196
Phase: Phase 1
Role: Lead Sponsor
Start: Jul 12, 2020
Completion: Jan 29, 2021
NCT04479644
Safety, Tolerability, and Pharmacokinetics Study of Human Monoclonal Antibody BRII-198
Start: Jul 13, 2020
Completion: Feb 3, 2021
NCT04501978
ACTIV-3: Therapeutics for Inpatients With COVID-19
Phase: Phase 3
Role: Collaborator
Start: Aug 4, 2020
Completion: Jul 14, 2023
NCT04507269
Study of VIR-2218 in Patients With Chronic Hepatitis B in Mainland China
Phase: Phase 2
Start: Aug 18, 2020
Completion: Sep 30, 2021
NCT04518410
ACTIV-2: A Study for Outpatients With COVID-19
Phase: Phase 2/3
Start: Aug 19, 2020
Completion: Jun 20, 2023
NCT05780424
BRII-196/BRII-198 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
Start: Dec 16, 2020
Completion: Oct 10, 2022
NCT04691180
A Phase 1 Study of Human Monoclonal Antibodies, BRII-196 and BRII-198
Start: Jan 5, 2021
Completion: Sep 16, 2021
NCT04770467
A Safety and Efficacy Study of Human Monoclonal Antibodies, BRII-196 and BRII-198 for the Treatment of Patients With COVID-19
Start: Feb 28, 2021
Completion: Oct 31, 2022
NCT04749368
Study to Investigate the Safety and Efficacy of BRII-835 and BRII-179 Combination Therapy Treating Chronic Hepatitis B Virus (HBV) Infection
Start: Apr 12, 2021
Completion: Jul 4, 2023
NCT04787211
A Study of Human Monoclonal Antibodies, BRII-196 and BRII-198
Start: Jun 20, 2021
Completion: Dec 2, 2021
NCT05845840
A Study of BRII-297 in Healthy Adult Subjects
Start: May 15, 2023
Completion: Jan 17, 2024
NCT05970289
Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV Patients
Start: Aug 22, 2023
Completion: Feb 28, 2026
NCT06057012
A Study of BRII-296 in Adults With Severe Postpartum Depression (PPD)
Start: Sep 29, 2023
Completion: Mar 13, 2024
NCT06491563
Study to Investigate the Efficacy and Safety of Regimens Containing BRII-179, BRII-835, and PEG-IFNα Treating Chronic Hepatitis B Virus (HBV) Infection (ENRICH)
Start: Aug 6, 2024
Completion: Jun 30, 2027
NCT06650852
A Study to Evaluate the Efficacy and Safety of Combination Therapy of BRII-179, BRII-835 and PEG-IFNα in Participants With Chronic Hepatitis B Virus (HBV) Infection (ENHANCE)
Start: Oct 31, 2024
Completion: Jul 31, 2027
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