Oncolytic Vaccines
Total Trials
13
As Lead Sponsor
11
As Collaborator
2
Total Enrollment
819
NCT01238107
A Clinical Study With MT-102 in Subjects With Cancer Cachexia
Phase: Phase 2
Role: Lead Sponsor
Start: Apr 30, 2011
Completion: May 31, 2013
NCT02028442
Phase I / II Study of Enadenotucirev by Sub-acute Fractionated IV Dosing in Cancer Patients
Phase: Phase 1/2
Start: Sep 20, 2012
Completion: Apr 29, 2016
NCT02053220
Mechanism of Action Trial of ColoAd1
Phase: Phase 1
Start: Jun 30, 2013
Completion: Apr 30, 2016
NCT02028117
Phase I / Dose Expansion Study of Enadenotucirev in Ovarian Cancer Patients
Start: Jun 30, 2014
Completion: Nov 19, 2019
NCT02636036
Phase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial Tumors
Start: Jan 25, 2016
Completion: Oct 8, 2021
NCT03852511
First in Human Study of NG-350A (an Oncolytic Adenoviral Vector Which Expresses an Anti-CD40 Antibody)
Start: Feb 19, 2019
Completion: Feb 4, 2022
NCT03916510
Chemoradiation With Enadenotucirev as a Radiosensitiser in Locally Advanced Rectal Cancer
Role: Collaborator
Start: Jul 29, 2019
Completion: Feb 24, 2023
NCT04053283
First in Human Study With NG-641, a Tumour Selective Transgene Expressing Adenoviral Vector
Start: Jan 23, 2020
Completion: Dec 20, 2023
NCT04787991
Exploratory Platform Trial to Evaluate Immunotherapy Combinations With Chemotherapy for the Treatment of Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma
Start: Aug 9, 2021
Completion: Jan 11, 2025
NCT04830592
A Study of NG-641 and Pembrolizumab in Squamous Cell Carcinoma of the Head and Neck
Start: Nov 4, 2021
Completion: Oct 4, 2024
NCT05043714
Study of NG-641 in Combination With Nivolumab in Metastatic or Advanced Epithelial Tumours
Start: Dec 1, 2021
NCT05165433
Study of NG-350A Plus Pembrolizumab in Metastatic or Advanced Epithelial Tumours (FORTIFY)
Start: Apr 13, 2022
Completion: Aug 29, 2025
NCT06459869
NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer
Start: Apr 7, 2025
Completion: Jan 30, 2029
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