Antibody discovery & engineering
Total Trials
12
As Lead Sponsor
7
As Collaborator
5
Total Enrollment
1,067
NCT03707093
Study of CD137 Agonist ADG106 With Advanced or Metastatic Solid Tumors and/or Non-Hodgkin Lymphoma
Phase: Phase 1
Role: Lead Sponsor
Start: Sep 17, 2018
Completion: Sep 30, 2022
NCT04111445
Study of ADG116 in Patients With Advanced/Metastatic Solid Tumors
Start: Aug 29, 2019
Completion: Apr 27, 2021
NCT04501276
A Phase 1b/2 Study of ADG116, ADG116 Combined With Anti-PD-1 Antibody or Anti-CD137 Antibody in Solid Tumors Patients
Start: Sep 23, 2020
Completion: Feb 1, 2025
NCT04524871
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)
Phase: Phase 1/2
Role: Collaborator
Start: Nov 1, 2020
Completion: Dec 31, 2026
NCT04645069
ADG126, ADG126 in Combination With Anti PD1 Antibody, and ADG126 in Combination With ADG106 in Advanced/Metastatic Solid Tumors
Start: Mar 15, 2021
Completion: May 17, 2024
NCT05236608
A Study to Evaluate the Combination of Nivolumab With ADG106 in Metastatic NSCLC
Start: Nov 12, 2021
Completion: May 31, 2024
NCT05277402
ADG116 in Combination With Pembrolizumab in Patients With Advanced/Metastatic Solid Tumors
Start: Feb 9, 2022
Completion: Dec 1, 2022
NCT05275777
A Phase Ib Safety lead-in, Followed by Phase II Trial of ADG106 in Combination With Neoadjuvant Chemotherapy in HER2 Negative Breast Cancer
Start: May 19, 2022
Completion: Feb 28, 2030
NCT05405595
ADG126 in Combination With Pembrolizumab in Patients With Advanced/Metastatic Solid Tumors
Start: Jun 15, 2022
Completion: Apr 30, 2027
NCT05614258
Study of ADG206 in Subjects With Advanced/Metastatic Solid Tumors
Start: Feb 13, 2023
Completion: Oct 31, 2025
NCT05491083
Pembrolizumab and ADG106 in Advanced Solid Cancers and Triple Negative Breast Cancer
Start: Jun 12, 2023
NCT06846268
Neoadjuvant ADG126 and Pembrolizumab in Locally Advanced Colorectal Cancer
Phase: Phase 2
Start: Apr 14, 2025
Completion: Dec 31, 2027
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