Defunct Company
Total Trials
48
As Lead Sponsor
33
As Collaborator
15
Total Enrollment
33,944
NCT00417378
Efficacy Study of LV Assist Device to Treat Patients With Cardiogenic Shock (ISAR-SHOCK)
Phase: Phase 4
Role: Collaborator
Start: Aug 31, 2004
Completion: Mar 31, 2006
NCT00534859
PROTECT I, A Prospective Feasibility Trial Investigating the Use of IMPELLA RECOVER LP 2.5 System in Patients Undergoing High Risk PCI
Phase: Phase 2
Role: Lead Sponsor
Start: Aug 31, 2006
Completion: Mar 31, 2011
NCT00596726
RECOVER I Impella RECOVER LP/LD 5.0 Support System Safety and Feasibility Study
Completion: May 31, 2010
NCT00562016
Protect II, A Prospective, Multicenter Randomized Controlled Trial
Phase: Phase 3
Start: Oct 31, 2007
Completion: Sep 30, 2011
NCT00971776
Voyager I: Patient Discharge Using the AB5000 Portable Driver System
Start: Jun 30, 2008
Completion: Sep 30, 2013
NCT00972270
Trial Using Impella LP 2.5 System in Patients With Acute Myocardial Infarction Induced Hemodynamic Instability
Start: Jul 31, 2008
Completion: Sep 30, 2010
NCT01185691
Investigating the Role of Impella 2.5 System in Acutely Decompensated Chronic Heart Failure Patients
Phase: N/A
Start: Jul 31, 2010
Completion: Dec 31, 2012
NCT01294267
Percutaneous Hemodynamic Support With Impella 2.5 During Scar-related Ventricular Tachycardia Ablation
Start: Sep 30, 2010
Completion: Jan 31, 2012
NCT01319760
MINI-AMI: Minimizing Infarct Size With Impella 2.5 Following PCI for Acute Myocardial Infarction
Start: Apr 30, 2011
Completion: Mar 31, 2013
NCT01543022
Symphony: The Implantable Counter Pulsation Device (CPD) Safety and Feasibility Trial
Phase: Phase 1/2
Start: Nov 30, 2011
Completion: Jun 30, 2014
NCT01777607
The Use of Impella RP Support System in Patients With Right Heart Failure
Start: May 31, 2013
Completion: Jun 30, 2016
NCT02831881
Protected PCI Study
Start: Nov 30, 2015
Completion: Not specified
NCT03677180
National Cardiogenic Shock Initiative
Start: May 19, 2016
Completion: Dec 31, 2020
NCT03000270
Door To Unloading With IMPELLA CP System in Acute Myocardial Infarction - Safety and Feasibility Study
Start: Apr 11, 2017
Completion: Aug 16, 2018
NCT04136392
The Global cVAD Study
Start: Jul 14, 2017
Completion: Jan 31, 2026
NCT04682483
Cardiogenic Shock Working Group Registry
Start: Dec 4, 2017
Completion: Jun 1, 2026
NCT03836079
SVC Occlusion in Subjects With Acute Decompensated Heart Failure
Start: Jul 31, 2019
Completion: Feb 18, 2025
NCT04648306
Restore EF Observational Study
Start: Sep 1, 2019
Completion: Sep 30, 2021
NCT03947619
Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: The STEMI-DTU Trial
Start: Dec 12, 2019
Completion: Oct 31, 2030
NCT04321148
Protect Kidney Trial
Start: Jan 24, 2020
Completion: Dec 31, 2023
NCT05100836
SURPASS Impella 5.5 Study
Start: Sep 21, 2020
Completion: May 14, 2025
NCT04477603
Impella ECP Early Feasibility Study
Start: Oct 9, 2020
Completion: Oct 31, 2026
NCT04465201
The Smart Pump Study
Start: Nov 2, 2020
Completion: Dec 31, 2022
NCT04234659
PPCM Observational Study (Peripartum Cardiomyopathy)
Start: Jan 11, 2021
Completion: Feb 1, 2023
NCT05473130
Breethe Abiomed Recovery RegisTry (BART)
Start: Mar 31, 2021
Completion: Apr 2, 2024
NCT04763200
Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function
Start: Apr 13, 2021
Completion: Oct 31, 2027
NCT04681313
Pressure-Volume Loop During High-Risk PCI
Start: Apr 19, 2021
Completion: Sep 12, 2024
NCT04928118
Hemodynamic Effects Of Impella On Renal Circulation And Risk Of CA-AKI Among Patients Undergoing Protected PCI
Start: Jan 31, 2022
Completion: Oct 31, 2024
NCT05291884
Use of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility Study
Start: Apr 20, 2022
Completion: Mar 31, 2028
NCT04339452
Impella Supported OPCABG
Start: May 11, 2022
Completion: Mar 31, 2026
NCT05800951
Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock
Start: Jul 22, 2022
Completion: Dec 31, 2025
NCT05466552
The PROTECT-EU Study
Start: Oct 18, 2022
Completion: Jun 1, 2024
NCT05820451
Impella Real-World Surveillance of Patients Using Sodium Bicarbonate
Start: Dec 15, 2022
Completion: Feb 22, 2024
NCT05334784
Impella ECP Study (ECP Study) and Impella ECP Continued Access Protocol
Start: Dec 20, 2022
Completion: Dec 31, 2026
NCT05756751
IMPACT EU Post-Market Clinical Follow-Up Study
Start: Apr 27, 2023
Completion: Aug 8, 2026
NCT05529654
IMpella-Protected cArdiaC Surgery Trial (IMPACT)
Start: Sep 21, 2023
Completion: Oct 31, 2025
NCT05064202
Unloading in Heart Failure Cardiogenic Shock
Start: Oct 1, 2023
Completion: Jul 1, 2028
NCT05759377
V-A ECMO AUTO Mode Registry
Start: Oct 11, 2023
Completion: Jun 3, 2025
NCT05506449
The RECOVER IV Trial
Start: Oct 28, 2023
Completion: Dec 6, 2024
NCT05782491
Awake Axillary Impella 5.5 Placement - A Feasibility Trial
Start: Apr 30, 2024
Completion: Jul 18, 2024
NCT06637644
Impella RP Flex with Smart Assist
Start: May 29, 2024
NCT06308055
Abiomed Impella RT-DAQ - Observational Study
Start: Oct 4, 2024
Completion: Sep 30, 2026
NCT06800716
Impella Reverse Remodeling in End-Stage Heart Failure
Start: Dec 4, 2024
Completion: Nov 30, 2027
NCT06487091
Platelet Function and Impella Support
Start: Feb 24, 2025
Completion: Jan 31, 2027
NCT06964685
Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Start: Jul 10, 2025
Completion: Oct 30, 2028
NCT06765226
Impella Pump Return Study to Analyze Deposits and Biomaterial in Used Pumps
Start: Sep 21, 2025
Completion: Jan 31, 2031
NCT06965504
INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
Start: Dec 1, 2025
Completion: Jun 1, 2028