Clinical Trials for Novartis

Explore 508 clinical trials worldwide

Showing 1-50 of 508 trials

Active filters:Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruitingSponsor: Novartis

Clinical Trials (508)

NCT06881823
Study to Assess [177Lu]Lu-PSMA-R2 (AAA602) and [225Ac]Ac-PSMA-R2 (AAA802) in Participants With PSMA-positive HRLPC
PHASE1/PHASE2Not yet recruiting
228 participants
Started: Jun 29, 2026 · Completed: Jun 1, 2033
1 condition1 sponsor0 locations
NCT06851845
Clinical Outcomes of C3 Glomerulopathy and IC-MPGN in Russia: Hybrid Retrospective - Prospective Study
N/ANot yet recruiting
100 participants
Started: Feb 1, 2026 · Completed: Feb 1, 2028
1 condition1 sponsor0 locations
NCT05776927
A Study to Evaluate the Efficacy and Safety of QVM149 (Indacaterol Acetate / Glycopyrronium Bromide / Mometasone Furoate) Versus Salmeterol Xinafoate/Fluticasone Propionate in Children From 12 Years to Less Than 18 Years of Age With Asthma.
PHASE3Not yet recruiting
304 participants
Started: Feb 1, 2026 · Completed: Feb 1, 2029
1 condition1 sponsor0 locations
NCT07190053
Long Term Treatment Strategies and Effectiveness of Secukinumab in Patient With JIA Subtypes of JPsA and ERA: Study From German BIKER Registry.
N/ANot yet recruiting
100 participants
Started: Dec 31, 2025 · Completed: Sep 18, 2029
2 conditions1 sponsor0 locations
NCT07174063
A Phase I Study of JSB462 (Luxdegalutamide) in Japanese Patients With Metastatic Prostate Cancer
PHASE1Not yet recruiting
15 participants
Started: Dec 26, 2025 · Completed: Jun 18, 2027
1 condition1 sponsor0 locations
NCT06994845
Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients With Primary IgAN
PHASE3Not yet recruiting
24 participants
Started: Dec 8, 2025 · Completed: Jun 30, 2030
1 condition1 sponsor3 locations
NCT07025512
177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and Cytopenia
PHASE2Not yet recruiting
40 participants
Started: Dec 3, 2025 · Completed: Jun 30, 2029
4 conditions2 sponsors1 location
NCT06964958
LASER - a Phase 2 Trial of 177Lu-PSMA-617 as Systemic Therapy for Renal Cell Carcinoma
PHASE2Not yet recruiting
24 participants
Started: Nov 30, 2025 · Completed: Dec 1, 2028
3 conditions2 sponsors2 locations
NCT07206056
An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)
PHASE1/PHASE2Recruiting
188 participants
Started: Nov 28, 2025 · Completed: Dec 17, 2030
1 condition1 sponsor2 locations
NCT07146906
A Study to Assess the Effects of Zigakibart on IgA Nephropathy.
PHASE2Not yet recruiting
32 participants
Started: Nov 18, 2025 · Completed: Jul 16, 2030
1 condition1 sponsor0 locations
NCT06997159
A Clinical Trial to Investigate Efficacy, Safety and Pharmacokinetics (PK) of Two LXE408 Oral Regimens and Oral Miltefosine as Active Control in Participants Aged ≥ 18 Years Old With Localized Cutaneous Leishmaniasis in the Region of the Americas (AMR).
PHASE2Not yet recruiting
250 participants
Started: Nov 16, 2025 · Completed: Jul 10, 2027
1 condition2 sponsors5 locations
NCT07091019
A Real-world Chronic Myelogenous Leukemia (CML) Patient Disease Registry to Describe Patient Experience and Clinical Outcomes Among Patients With CML Receiving Approved First or Second Line Tyrosine Kinase Inhibitor (TKI) Therapy
N/ANot yet recruiting
1,000 participants
Started: Nov 15, 2025 · Completed: May 15, 2033
1 condition1 sponsor0 locations
NCT07190300
TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
PHASE1/PHASE2Not yet recruiting
203 participants
Started: Nov 3, 2025 · Completed: May 14, 2032
1 condition1 sponsor0 locations
NCT07136428
Asciminib in HER2+ Breast Cancer Brain Metastases
PHASE1/PHASE2Not yet recruiting
42 participants
Started: Nov 1, 2025 · Completed: Nov 1, 2032
1 condition2 sponsors0 locations
NCT07150715
Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide With Metastasis-Directed Stereotactic Body Radiotherapy for the Treatment of Recurrent, Oligometastatic Prostate Adenocarcinoma
PHASE2Not yet recruiting
107 participants
Started: Oct 31, 2025 · Completed: Oct 31, 2031
2 conditions2 sponsors1 location
NCT06751238
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).
PHASE1Recruiting
20 participants
Started: Oct 31, 2025 · Completed: Dec 1, 2032
1 condition1 sponsor3 locations
NCT07145177
177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer
PHASE1Not yet recruiting
30 participants
Started: Oct 31, 2025 · Completed: Aug 31, 2030
2 conditions2 sponsors1 location
NCT07217067
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
PHASE2Not yet recruiting
165 participants
Started: Oct 31, 2025 · Completed: Aug 20, 2027
1 condition1 sponsor0 locations
NCT07085767
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
PHASE3Not yet recruiting
1,000 participants
Started: Oct 31, 2025 · Completed: Jan 31, 2032
5 conditions2 sponsors10 locations
NCT07006727
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors
PHASE1Recruiting
96 participants
Started: Oct 16, 2025 · Completed: Jun 17, 2031
4 conditions1 sponsor2 locations
NCT07203001
A Phase II Trial to Evaluate the Clinical Efficacy, Safety and Tolerability of MAS825 in Pediatric and Adult Participants With Still's Disease
PHASE2Not yet recruiting
20 participants
Started: Oct 11, 2025 · Completed: May 2, 2029
1 condition1 sponsor0 locations
NCT06997588
EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)
PHASE2Recruiting
104 participants
Started: Oct 9, 2025 · Completed: Sep 30, 2030
1 condition1 sponsor2 locations
NCT07039422
Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab
PHASE2Not yet recruiting
60 participants
Started: Oct 3, 2025 · Completed: Aug 30, 2030
2 conditions1 sponsor0 locations
NCT07164976
Ribociclib for HR-positive HER2-negative Metastatic Breast Cancer
PHASE1/PHASE2Not yet recruiting
86 participants
Started: Oct 1, 2025 · Completed: Apr 1, 2030
1 condition2 sponsors0 locations
NCT07140614
A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of EDK060 in Adults With CMT1A.
PHASE1Recruiting
28 participants
Started: Sep 30, 2025 · Completed: Feb 26, 2028
1 condition1 sponsor2 locations
NCT07142265
Evaluation of 1-Year Clinical Outcomes With Early Inclisiran Initiation in Post-MI Patients
N/ANot yet recruiting
300 participants
Started: Sep 30, 2025 · Completed: Mar 31, 2027
1 condition1 sponsor0 locations
NCT07156149
Fabhalta Capsules Specified Drug-use Survey
N/ANot yet recruiting
50 participants
Started: Sep 30, 2025 · Completed: Jun 30, 2028
1 condition1 sponsor0 locations
NCT07102628
Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes
PHASE3Not yet recruiting
300 participants
Started: Sep 30, 2025 · Completed: Mar 6, 2027
1 condition1 sponsor0 locations
NCT07093801
Observational Study on Lutetium (177Lu) Vipivotide Tetraxetan to Treat Metastatic Castration Resistant Prostate Cancer
N/ANot yet recruiting
300 participants
Started: Sep 23, 2025 · Completed: May 23, 2029
1 condition1 sponsor0 locations
NCT06852820
68Ga-PSMA-11 PET-directed Radioligand Therapy in Metastatic Hepatocellular Carcinoma (HCC)
PHASE2Not yet recruiting
10 participants
Started: Sep 22, 2025 · Completed: Apr 1, 2027
3 conditions2 sponsors1 location
NCT07094516
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
PHASE2Not yet recruiting
407 participants
Started: Sep 18, 2025 · Completed: Dec 31, 2030
1 condition1 sponsor0 locations
NCT06894511
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI Versus AAA617 in PSMA Positive First-line mCRPC
PHASE2Recruiting
420 participants
Started: Sep 11, 2025 · Completed: Apr 9, 2029
1 condition1 sponsor5 locations
NCT06824103
Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With Corticosteroid-refractory Chronic Graft vs. Host Disease
PHASE4Recruiting
50 participants
Started: Sep 9, 2025 · Completed: Jan 11, 2032
3 conditions1 sponsor9 locations
NCT06955169
Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior Treatment
PHASE2Not yet recruiting
153 participants
Started: Aug 31, 2025 · Completed: Aug 31, 2030
1 condition2 sponsors0 locations
NCT06797531
RWE Non-Interventional Prospective Study of Ribociclib Effectiveness and Safety in Patients With HR+/HER2- Early Breast Cancer in Saudi Arabia
N/ARecruiting
177 participants
Started: Aug 27, 2025 · Completed: Nov 30, 2028
1 condition1 sponsor1 location
NCT07117214
A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers
PHASE1Not yet recruiting
36 participants
Started: Aug 20, 2025 · Completed: Jan 26, 2027
2 conditions1 sponsor0 locations
NCT06943495
Personalized vs. Fixed-Activity 177Lu-PSMA-617 Radiopharmaceutical Therapy (PRODIGY-2)
PHASE1Recruiting
60 participants
Started: Aug 15, 2025 · Completed: Mar 31, 2033
1 condition4 sponsors1 location
NCT06905301
Implementation Study to Describe and Compare Retention Rate and Adherence to Adjuvant Therapy With Ribociclib With and Without Usage of Mobile Application in Patients With HR+ HER2-negative Stage II and III Breast Cancer in Real-world Practice
N/ANot yet recruiting
240 participants
Started: Jul 31, 2025 · Completed: Jul 1, 2029
1 condition1 sponsor0 locations
NCT06930859
Non-interventional Study to Assess the Effectiveness and Safety of Ribociclib in the Adjuvant Therapy of Hormone Receptor Positive (HR+) HER2-negative Stage II and III Breast Cancer in Real Clinical Practice in Russia
N/ANot yet recruiting
2,883 participants
Started: Jul 31, 2025 · Completed: Jul 31, 2032
1 condition1 sponsor0 locations
NCT06770543
Leqvio rPMS (Regulatory Post-Marketing Surveillance in Korea)
N/ANot yet recruiting
1,500 participants
Started: Jul 31, 2025 · Completed: Jan 2, 2031
1 condition1 sponsor0 locations
NCT06639282
Repurposing Siponimod for Alzheimer's Disease
PHASE2Not yet recruiting
105 participants
Started: Jul 31, 2025 · Completed: Oct 31, 2029
4 conditions6 sponsors1 location
NCT06934967
Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients
PHASE3Not yet recruiting
12 participants
Started: Jul 28, 2025 · Completed: Oct 31, 2031
1 condition1 sponsor0 locations
NCT06858319
Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.
PHASE3Recruiting
223 participants
Started: Jul 28, 2025 · Completed: Jun 25, 2031
8 conditions1 sponsor1 location
NCT07036718
NIS PDC the Efficacy and Safety of Iptacopan in Adults in Routine Clinical Practice
N/ARecruiting
100 participants
Started: Jul 28, 2025 · Completed: Jan 31, 2028
1 condition1 sponsor1 location
NCT07032272
A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Severe Renal Impairment Compared to Matched Healthy Participants.
PHASE1Recruiting
16 participants
Started: Jul 23, 2025 · Completed: Nov 24, 2025
1 condition1 sponsor4 locations
NCT06846281
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
PHASE3Recruiting
360 participants
Started: Jul 23, 2025 · Completed: Jan 8, 2032
1 condition1 sponsor6 locations
NCT06909565
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
PHASE4Recruiting
6,000 participants
Started: Jul 23, 2025 · Completed: Dec 31, 2029
2 conditions4 sponsors5 locations
NCT06773936
Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia
PHASE2Not yet recruiting
55 participants
Started: Jul 15, 2025 · Completed: Jul 31, 2033
2 conditions2 sponsors0 locations
NCT06868212
A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines
PHASE3Recruiting
400 participants
Started: Jul 11, 2025 · Completed: Aug 3, 2027
1 condition1 sponsor59 locations
NCT06953882
Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy
PHASE2Recruiting
140 participants
Started: Jul 9, 2025 · Completed: Sep 30, 2030
1 condition3 sponsors1 location