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Clinical Trials for Io Therapeutics
Explore 19 clinical trials worldwide
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Showing 1-19 of 19 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Io Therapeutics
Clinical Trials (19)
NCT07123415
A Phase 1 Study of APX-343A as Monotherapy or in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
PHASE1
Not yet recruiting
110 participants
Started: Oct 31, 2025 · Completed: Dec 31, 2028
2 conditions
1 sponsor
0 locations
NCT07156565
Actinium Therapy for Late-stage Aggressive Sarcomas
PHASE1
Not yet recruiting
26 participants
Started: Oct 31, 2025 · Completed: Jan 31, 2032
1 condition
1 sponsor
0 locations
NCT07062198
Combined Metabolic Activator Supplementation in Subjects Diagnosed With Alzheimer's Disease
PHASE3
Recruiting
845 participants
Started: Sep 12, 2025 · Completed: Sep 30, 2026
1 condition
1 sponsor
9 locations
NCT06723171
Evaluation of Safety and Efficacy of IRX4204 in Mild to Moderate Plaque Psoriasis
PHASE2
Not yet recruiting
20 participants
Started: Jun 30, 2025 · Completed: Apr 30, 2026
3 conditions
1 sponsor
1 location
NCT06552169
REgulatory T Cell Therapy to Achieve Immunosuppression REduction
PHASE2
Recruiting
34 participants
Started: Jun 13, 2025 · Completed: Jun 30, 2031
1 condition
3 sponsors
4 locations
NCT06962098
Efficacy and Safety Study of Isuzinaxib in Subjects With DKD
PHASE2
Recruiting
186 participants
Started: May 26, 2025 · Completed: Jun 30, 2028
1 condition
1 sponsor
20 locations
NCT06158620
Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease
PHASE1/PHASE2
Recruiting
80 participants
Started: Mar 1, 2025 · Completed: Dec 1, 2026
4 conditions
2 sponsors
1 location
NCT06671236
Clinical Study of Regulatory T Cells (Tregs) in the Treatment of Neurodegenerative Diseases
PHASE1
Recruiting
12 participants
Started: Nov 21, 2024 · Completed: Dec 31, 2027
1 condition
2 sponsors
1 location
NCT06631092
Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Neoadjuvant Triple-negative Breast Cancer
PHASE1/PHASE2
Recruiting
8 participants
Started: Nov 20, 2024 · Completed: Dec 31, 2028
1 condition
2 sponsors
2 locations
NCT06631079
Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Anti-PD-1/PD-L1 Therapy in Patients With Solid Tumors
PHASE1/PHASE2
Recruiting
20 participants
Started: Oct 7, 2024 · Completed: Dec 31, 2028
1 condition
2 sponsors
8 locations
NCT06146257
A Study of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher Risk Myelodysplastic Syndromes
PHASE1
Recruiting
48 participants
Started: Jan 11, 2024 · Completed: Oct 8, 2026
2 conditions
1 sponsor
8 locations
NCT05758896
Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI
PHASE2
Recruiting
280 participants
Started: Dec 27, 2023 · Completed: Dec 31, 2024
1 condition
1 sponsor
14 locations
NCT05724576
Intracoronary Administration of OmniMSC-AMI for Acute ST-segment Elevation Myocardial Infarction Patients
PHASE1
Recruiting
10 participants
Started: Jun 26, 2023 · Completed: Mar 1, 2026
1 condition
1 sponsor
1 location
NCT05789069
A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
PHASE1
Recruiting
83 participants
Started: May 9, 2023 · Completed: Dec 31, 2025
5 conditions
1 sponsor
11 locations
NCT05726864
A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors
PHASE1/PHASE2
Active, not recruiting
158 participants
Started: Apr 14, 2023 · Completed: Nov 30, 2026
14 conditions
1 sponsor
28 locations
NCT05394064
A Study to Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN)
PHASE1/PHASE2
Active, not recruiting
16 participants
Started: Nov 17, 2022 · Completed: Mar 30, 2029
3 conditions
1 sponsor
2 locations
NCT05238883
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
PHASE1
Recruiting
170 participants
Started: Mar 10, 2022 · Completed: Dec 31, 2026
9 conditions
1 sponsor
10 locations
NCT05008874
Study of Disease Progression in Adults With Inherited Forms of Spastic Paraplegia
N/A
Active, not recruiting
65 participants
Started: Jun 21, 2021 · Completed: Jun 1, 2028
3 conditions
1 sponsor
6 locations
NCT04162353
BCMA-CD19 cCAR in Multiple Myeloma and Plasmacytoid Lymphoma
PHASE1
Recruiting
12 participants
Started: Jul 1, 2019 · Completed: Jul 31, 2026
3 conditions
3 sponsors
2 locations