A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

158

Participants

Timeline

Start Date

April 14, 2023

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Pancreatic Ductal AdenocarcinomaColorectal CancerKRAS G12DKRAS G12RKRAS G12VKRAS G12AKRAS G12CKRAS G12SKRAS G13DNRAS G12DNRAS G12RNRAS G12VNRAS G12CNRAS G12S
Interventions
DRUG

ELI-002 7P

ELI-002 Amph-CpG-7909 admixed with ELI-002 Amph-Peptides 7P administered via SC injection weekly for 4 consecutive weeks, followed by bi-weekly injections over 4 weeks, during the Immunization Period; additional SC injections weekly for 4 weeks during the Booster Period (the two periods are separated by 2 months of no dosing)

Trial Locations (28)

10022

Memorial Sloan Kettering Cancer Center, New York

10065

New York Presbyterian Weill Cornell Medical Center, New York

11042

Northwell Health, Lake Success

18003

Lehigh Valley Health Network, Allentown

19104

University of Pennsylvania, Philadelphia

30322

Emory Winship Cancer Institute, Atlanta

32224

Mayo Clinic Comprehensive Cancer Center, Jacksonville

32610

University of Florida Health Cancer Center, Gainesville

33124

University of Miami, Coral Gables

33612

Moffitt Cancer Center, Tampa

37203

Sarah Cannon Research Institute, Nashville

37212

Vanderbilt University Medical Center, Nashville

48109

University of Michigan, Ann Arbor

52242

University of Iowa, Iowa City

53226

Medical College of Wisconsin, Milwaukee

55905

Mayo Clinic Comprehensive Cancer Center, Rochester

70121

Ochsner Health, New Orleans

75390

University of Texas Southwestern, Dallas

77030

The University of Texas MD Anderson Cancer Center, Houston

80045

University of Colorado Hospital-Anschutz Cancer Pavillion, Aurora

85054

Mayo Clinic Comprehensive Cancer Center, Phoenix

85234

Banner MD Anderson Cancer Center, Gilbert

90048

Cedars-Sinai Medical Center, Los Angeles

90095

University of California Los Angeles, Los Angeles

91010

City of Hope, Duarte

92868

University of California, Irvine, Orange

02210

Massachusetts General Hospital, Boston

02215

Dana Farber Cancer Institute, Boston

Sponsors
All Listed Sponsors
lead

Elicio Therapeutics

INDUSTRY

NCT05726864 - A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors | Biotech Hunter | Biotech Hunter