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Clinical Trials for Essen Biotech
Explore 15 clinical trials worldwide
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Showing 1-15 of 15 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Essen Biotech
Clinical Trials (15)
NCT07066982
Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas
PHASE1/PHASE2
Recruiting
60 participants
Started: May 29, 2025 · Completed: Dec 28, 2028
9 conditions
1 sponsor
1 location
NCT07032129
Sequential CAR-T Cells Targeting BCMA/GPRC5D in Patients With Relapsed/ Refractory Multiple Myeloma
PHASE1/PHASE2
Recruiting
60 participants
Started: Apr 29, 2025 · Completed: Dec 28, 2028
4 conditions
1 sponsor
1 location
NCT07066995
Mesothelin and Claudin 18.2 Dual-Target CAR-T Therapy in Advanced Pancreatic Cancer
PHASE1/PHASE2
Recruiting
60 participants
Started: Apr 29, 2025 · Completed: Dec 28, 2028
4 conditions
1 sponsor
1 location
NCT07067255
Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer
PHASE1/PHASE2
Recruiting
80 participants
Started: Apr 29, 2025 · Completed: Dec 28, 2029
4 conditions
1 sponsor
1 location
NCT06640582
TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas
PHASE1/PHASE2
Recruiting
85 participants
Started: Oct 20, 2024 · Completed: Dec 28, 2026
7 conditions
1 sponsor
1 location
NCT06530303
Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer
PHASE1/PHASE2
Recruiting
85 participants
Started: Sep 29, 2024 · Completed: Dec 28, 2026
3 conditions
1 sponsor
1 location
NCT06532799
TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Stomach and Esophageal Cancer
PHASE1/PHASE2
Recruiting
75 participants
Started: Sep 10, 2024 · Completed: Dec 28, 2026
7 conditions
1 sponsor
1 location
NCT06532812
TIL Gean Therapy Combined With Immunotherapy for Advanced or Metastatic Refractory Breast Cancer
PHASE1/PHASE2
Recruiting
85 participants
Started: Aug 22, 2024 · Completed: Dec 28, 2026
4 conditions
1 sponsor
1 location
NCT06538012
TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Lung Cancer
PHASE1/PHASE2
Recruiting
85 participants
Started: Aug 20, 2024 · Completed: Dec 28, 2026
4 conditions
1 sponsor
1 location
NCT06399107
Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease
PHASE1/PHASE2
Recruiting
85 participants
Started: Aug 1, 2024 · Completed: Dec 28, 2025
2 conditions
1 sponsor
1 location
NCT06420076
Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD5/CD7-Specific CAR-T Cells
PHASE1/PHASE2
Recruiting
60 participants
Started: Jul 10, 2024 · Completed: Dec 28, 2026
6 conditions
1 sponsor
1 location
NCT06213636
Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia (PMBCL/CNS-BCL).
PHASE1/PHASE2
Recruiting
75 participants
Started: Jul 10, 2024 · Completed: Dec 10, 2028
7 conditions
1 sponsor
1 location
NCT06350110
Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)
PHASE1/PHASE2
Recruiting
75 participants
Started: Jul 10, 2024 · Completed: Dec 28, 2025
9 conditions
1 sponsor
1 location
NCT06420063
Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AML
PHASE1/PHASE2
Recruiting
85 participants
Started: Jul 10, 2024 · Completed: Dec 28, 2026
4 conditions
1 sponsor
1 location
NCT06428188
Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune Diseases
PHASE1/PHASE2
Recruiting
60 participants
Started: May 29, 2024 · Completed: Dec 28, 2026
4 conditions
1 sponsor
1 location