Clinical Trials for A2 Biotherapeutics

Explore 5 clinical trials worldwide

Showing 1-5 of 5 trials

Active filters:Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruitingSponsor: A2 Biotherapeutics

Clinical Trials (5)

NCT06885424
A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products
N/AEnrolling by invitation
400 participants
Started: Aug 31, 2025 · Completed: Mar 31, 2040
15 conditions1 sponsor2 locations
NCT06682793
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
PHASE1/PHASE2Recruiting
240 participants
Started: May 22, 2025 · Completed: Mar 31, 2030
17 conditions1 sponsor10 locations
NCT06051695
A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
PHASE1/PHASE2Recruiting
230 participants
Started: Apr 3, 2024 · Completed: Jun 30, 2029
20 conditions2 sponsors11 locations
NCT05736731
A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
PHASE1/PHASE2Active, not recruiting
160 participants
Started: Apr 28, 2023 · Completed: Dec 31, 2026
16 conditions2 sponsors8 locations
NCT04981119
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
N/ARecruiting
200 participants
Started: Oct 29, 2021 · Completed: Dec 31, 2026
17 conditions2 sponsors15 locations