Impact of Phenylalanine Elevations on Brain and Cognition in Adult PKU Carriers

NARecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

April 30, 2027

Study Completion Date

April 30, 2027

Conditions
Carrier of PhenylketonuriaHealthy
Interventions
DIETARY_SUPPLEMENT

Phenylalanine (Phe)

Oral ingestion of phenylalanine (Phe)

DIETARY_SUPPLEMENT

Placebo

Oral ingestion of Placebo (Vitamin C)

Trial Locations (1)

65201

RECRUITING

University of Missouri-Columbia, Columbia

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

University of Missouri-Columbia

OTHER

NCT07220265 - Impact of Phenylalanine Elevations on Brain and Cognition in Adult PKU Carriers | Biotech Hunter | Biotech Hunter