Accelerated iTBS Targeting of Working Memory Versus Inhibitory Control in Adolescent ADHD

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

September 1, 2029

Study Completion Date

September 1, 2029

Conditions
ADHD
Interventions
DEVICE

intermittent theta burst stimulation (iTBS)

Device: Stimulation will be delivered using a Nexstim NBT System 2 device. Motor Threshold: The iTBS pulse intensity will be set at 80% of resting motor threshold (MT). The iTBS protocol will administer 2-second trains with an 8-second inter-burst interval for 1800 pulses \[600 bursts\]), in 50 Hz bursts at 5 Hz (i.e., 200 ms intervals). Each session will last approximately nine minutes. As three sessions will be administered per day, there will be a 20-30 minutes break between each of the nine-minute iTBS sessions. Magnetic pulses will be delivered in an MRI neuro-navigated manner using a cooled figure-eight coil. The PreSMA target will be approximately defined based on MNI coordinates: 13, 18, 62. The left DLPFC target will be approximately defined based on MNI coordinates: -44, 28, 16.

Trial Locations (1)

02915

RECRUITING

E. P. Bradley Hospital, East Providence

All Listed Sponsors
lead

Bradley Hospital

OTHER

NCT07219810 - Accelerated iTBS Targeting of Working Memory Versus Inhibitory Control in Adolescent ADHD | Biotech Hunter | Biotech Hunter