Intervention for Communication Quality of Life in Primary Progressive Aphasia

NARecruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

January 3, 2026

Primary Completion Date

August 31, 2027

Study Completion Date

August 31, 2027

Conditions
Primary Progressive Aphasia(PPA)Semantic DementiaLogopenic Progressive Aphasia (LPA)Nonfluent Aphasia, ProgressiveProgressive AphasiaSemantic Variant Primary Progressive Aphasia (svPPA)Semantic AphasiaLogopenic Variant Primary Progressive AphasiaLogopenic Variant of Primary Progressive Aphasia (LPA)Logopenic Progressive AphasiaNonfluent Variant Primary Progressive Aphasia (nfvPPA)Nonfluent Progressive Aphasia
Interventions
BEHAVIORAL

Multicomponent Lexical Retrieval Training

In person or via teletherapy: A multi-component treatment incorporating elements of restitutive, compensatory, and care-partner focused interventions. Participants work on producing names of personally relevant target in multiple communication modalities. Biweekly (approximately one hour each) sessions with a clinician target multimodal communication and the use of strategies to support word retrieval. These skills are also trained via daily independent practice. The participant meets four times during the course of treatment with a study partner (e.g., spouse) for communication counseling, education, and practice of communication strategies.

BEHAVIORAL

Multicomponent Video Implemented Script Training in Aphasia

In person or via teletherapy: A multi-component treatment incorporating elements of restitutive, compensatory, and care-partner focused interventions. Treatment focuses on production of individually-tailored, personally relevant scripts. The participant completes 30 minutes per day of independent practice, during which they speak in unison with a video model. Biweekly (approximately one hour each) sessions with a clinician target clear and accurate script production, memorization, and conversational usage, as well as multimodal communication. The participant meets 6 times during the course of treatment with a study partner (e.g., spouse) for communication counseling, education, and practice of communication strategies.

Trial Locations (1)

78712

RECRUITING

University of Texas, Austin

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Institute on Aging (NIA)

NIH

lead

University of Texas at Austin

OTHER