165
Participants
Start Date
November 1, 2025
Primary Completion Date
May 1, 2027
Study Completion Date
October 1, 2027
Corticosteroid injection (CSI)
"A maximum of 3 joints will be treated with standard a standard combination of methylprednisolone and lidocaine:~* 1st Carpometacarpal (CMC) joint - 20 mg methylprednisolone/0.5 mL 1% lidocaine\*~* Radiocarpal (RC) joint - 40 mg methylprednisolone/1 mL 1% lidocaine\*~* Scaphotrapeziotrapezoidal (STT) joint - 20 mg methylprednisolone/0.5 mL 1% lidocaine\*~* Metacarpophalangeal (MCP) joint - 20 mg methylprednisolone/0.5 mL 1% lidocaine~* Interphalangeal (IP) joint - 10 mg methylprednisolone/0.25 mL 1% lidocaine"
Low-dose radiotherapy (LDRT)
"Subjects will be treated with low-dose radiotherapy of 300cGy in 6 fractions, 2-3 times per week on non-consecutive days.~Non-responders to the initial LDRT treatment will receive a second treatment course of 300cGy in 6 fractions to be given 2-3 times per week on non-consecutive days."
RECRUITING
Mayo Clinic in Rochester, Rochester
Lead Sponsor
Mayo Clinic
OTHER