125
Participants
Start Date
November 3, 2025
Primary Completion Date
May 31, 2030
Study Completion Date
May 31, 2031
Multisensory early oral administration of human milk
M-MILK is implemented starting on day 3 of life, during the day shift, after every hands-on care, during the beginning of a full gavage feeding, and up to 4 times a day. Infants receive M-MILK in small droplets via a 1-ml syringe. M-MILK will cease upon oral feeding initiation. Infants will receive either mother's own milk or donor's milk based on availability. Infants may receive up to 1 mL of milk each time based on their cues and responses. The 1 mL volume intake is included as part of their oral caloric intake. M-MILK is provided by research nurses or parents.
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Rush University Medical Center
OTHER
Loyola University
OTHER