Multisensory Early Oral Administration of Human Milk (M-MILK) for Very Preterm Infants

NANot yet recruitingINTERVENTIONAL
Enrollment

125

Participants

Timeline

Start Date

November 3, 2025

Primary Completion Date

May 31, 2030

Study Completion Date

May 31, 2031

Conditions
Infant, Premature, Diseases
Interventions
OTHER

Multisensory early oral administration of human milk

M-MILK is implemented starting on day 3 of life, during the day shift, after every hands-on care, during the beginning of a full gavage feeding, and up to 4 times a day. Infants receive M-MILK in small droplets via a 1-ml syringe. M-MILK will cease upon oral feeding initiation. Infants will receive either mother's own milk or donor's milk based on availability. Infants may receive up to 1 mL of milk each time based on their cues and responses. The 1 mL volume intake is included as part of their oral caloric intake. M-MILK is provided by research nurses or parents.

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

Rush University Medical Center

OTHER

lead

Loyola University

OTHER

NCT07216664 - Multisensory Early Oral Administration of Human Milk (M-MILK) for Very Preterm Infants | Biotech Hunter | Biotech Hunter