LT Comparative Effectiveness of 2 Caries Treatments

NANot yet recruitingINTERVENTIONAL
Enrollment

480

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

January 31, 2030

Study Completion Date

January 31, 2030

Conditions
Dental Caries
Interventions
DEVICE

"A simple medical strategy consisting of silver diamine fluoride (SDF)"

Bi-annual topical application of 38% silver diamine solution to new ICDAS lesions code 3-6. Advantage Arrest, Elevate Oral Care, West Palm Beach FL

DEVICE

"A typical dental strategy consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride Varnish (FV)"

GC Fuji (for ART) and FluoriMax Varnish. Atraumatic Restoration Treatment (ART) to new ICDAS lesions code 3-6, followed by bi-annual topical fluoride varnish (FV) to all teeth.

Trial Locations (1)

44106

Case Western Reserve University, Cleveland

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

lead

Case Western Reserve University

OTHER

NCT07213661 - LT Comparative Effectiveness of 2 Caries Treatments | Biotech Hunter | Biotech Hunter